MetaCap

Upstream Bio (UPB) vs Veraxa Biotech (VRXA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

Upstream Bio (UPB) has outperformed Veraxa Biotech (VRXA) over the past year, losing 86.8% versus a loss of 89.4%. Veraxa Biotech is the larger company by market cap ($157.0 million vs $151.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

UPB-86.84%VRXA-89.43%
+147%+23%-101%
Oct 17, 20251 yearOct 16, 2026
UPB-87.45%VRXA-88.90%
+109%+6%-98%
Oct 7, 20245 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

UPB versus VRXA key metrics
MetricUPBVRXA
Share price$2.76$1.11
Market cap$151.17M$156.96M
1-day change-18.10%+0.91%
YTD return-89.83%-89.60%
1-year return-86.84%-89.43%
EPS (TTM)$-2.88$-0.57
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$2.85M—
Revenue growth (YoY)+20.42%—
Net income (latest FY)$-143.44M—
Operating margin-5618.82%—
Net margin-5026.03%—
52-week high$33.68$27.36
52-week low$2.74$1.04
Distance from 52-week high-91.81%-95.94%
Analyst consensusnone—
Avg. price target upside+1028.26%—
Average volume734.05K284.01K
Shares outstanding54.77M141.41M
Employees75—
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Upstream Bio

UPB stock →

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 75 employees

About Veraxa Biotech

VRXA stock →

VERAXA Biotech AG develops antibody-based therapeutics and antibody-drug conjugates for cancer treatment. The company develops antibody-based therapeutics, including antibody-drug conjugates and bispecific antibody formats, and offers a proprietary technology platform for functional antibody screening and bioconjugation.

Health Care · Biotechnology: Pharmaceutical Preparations

UPB vs VRXA FAQ

Which is bigger, Upstream Bio or Veraxa Biotech?

Veraxa Biotech (VRXA) is larger, with a market capitalization of $156.96M compared with $151.17M for Upstream Bio (UPB).

Which stock has performed better over the past year, UPB or VRXA?

UPB returned -86.84% over the past 12 months, compared with -89.43% for VRXA (price return, excluding dividends). Past performance does not predict future results.

Are Upstream Bio and Veraxa Biotech in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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