ACADIA Pharmaceuticals (ACAD) vs Tango Therapeutics (TNGX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Tango Therapeutics (TNGX) has outperformed ACADIA Pharmaceuticals (ACAD) over the past year, gaining 226.6% versus a loss of 8.1%. Over five years, TNGX leads with a +60.9% price change compared with +11.8% for ACAD. Tango Therapeutics is the larger company by market cap ($3.81 billion vs $3.37 billion), about 1.1 times the size.
ACADIA Pharmaceuticals converts more of its revenue into profit, with a net margin of 36.5% versus -162.9%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ACAD | TNGX |
|---|---|---|
| Share price | $19.58 | $22.57 |
| Market cap | $3.37B | $3.81B |
| 1-day change | -0.36% | +3.39% |
| YTD return | -26.69% | +154.74% |
| 1-year return | -8.12% | +226.63% |
| 5-year return | +11.82% | +60.87% |
| P/E ratio (TTM) | 8.78 | — |
| Forward P/E | 22.04 | — |
| EPS (TTM) | $2.23 | $-0.85 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $1.07B | $62.38M |
| Revenue growth (YoY) | +11.87% | +48.29% |
| Net income (latest FY) | $391.00M | $-101.59M |
| Gross margin | 91.69% | — |
| Operating margin | 9.78% | -178.39% |
| Net margin | 36.49% | -162.85% |
| 52-week high | $30.96 | $34.39 |
| 52-week low | $19.32 | $6.69 |
| Distance from 52-week high | -36.76% | -34.37% |
| Analyst consensus | buy | strong_buy |
| Avg. price target upside | +64.25% | +100.18% |
| Average volume | 1.85M | 2.65M |
| Shares outstanding | 172.31M | 168.61M |
| Employees | 796 | 137 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TNGX has outperformed ACAD by 234.7 percentage points over the past year.
- ACADIA Pharmaceuticals is more profitable, keeping 36.5 cents of every revenue dollar as net income versus -162.9 cents for Tango Therapeutics.
- Tango Therapeutics grew revenue faster in its latest fiscal year (+48.29% vs +11.87%).
About ACADIA Pharmaceuticals
ACAD stock →ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of medicines for neurological and rare disease in North America. The company offers NUPLAZID (pimavanserin), a selective serotonin inverse agonist/antagonist for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis; and DAYBUE, a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 to treat the symptoms of Rett syndrome by reducing neuroinflammation and supporting synaptic function.
Health Care · Biotechnology: Pharmaceutical Preparations · 796 employees
About Tango Therapeutics
TNGX stock →Tango Therapeutics, Inc., a precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need. The company develops methylthioadenosine -cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors, including TNG462, which is in Phase 1/2 clinical trial for treating pancreatic and lung cancer; and TNG456, a brain-penetrant PRMT5 inhibitor for the treatment of glioblastoma.
Health Care · Biotechnology: Pharmaceutical Preparations · 137 employees
ACAD vs TNGX FAQ
Which is bigger, ACADIA Pharmaceuticals or Tango Therapeutics?
Tango Therapeutics (TNGX) is larger, with a market capitalization of $3.81B compared with $3.37B for ACADIA Pharmaceuticals (ACAD).
Which stock has performed better over the past year, ACAD or TNGX?
TNGX returned +226.63% over the past 12 months, compared with -8.12% for ACAD (price return, excluding dividends). Past performance does not predict future results.
Are ACADIA Pharmaceuticals and Tango Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.