MetaCap

Alumis (ALMS) vs Helus Pharma (HELP)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Helus Pharma (HELP) has outperformed Alumis (ALMS) over the past year, gaining 71.2% versus a gain of 57.3%. Alumis is the larger company by market cap ($926.8 million vs $862.1 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ALMS+57.34%HELP+71.25%
+615%+273%-69%
Oct 8, 20251 yearOct 8, 2026
ALMS-47.59%HELP+4.10%
+133%+22%-89%
Jun 24, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ALMS versus HELP key metrics
MetricALMSHELP
Share price$7.16$11.80
Market cap$926.76M$862.11M
1-day change+2.73%+10.07%
YTD return-28.59%+31.05%
1-year return+57.34%+71.25%
5-year return—-85.68%
EPS (TTM)$-3.86$-4.15
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$31.35$15.15
52-week low$4.28$3.76
Distance from 52-week high-77.16%-22.11%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+348.74%+237.54%
Average volume2.44M1.77M
Shares outstanding129.44M73.06M
Employees237100
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • HELP has outperformed ALMS by 13.9 percentage points over the past year.

About Alumis

ALMS stock →

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases.

Health Care · Biotechnology: Pharmaceutical Preparations · 237 employees

About Helus Pharma

HELP stock →

Helus Pharma Inc., doing business as Helus Pharma, operates as a clinical stage pharmaceutical company that focuses on developing therapies to treat psychiatric and neurological conditions. It develops HLP003, a deuterated psilocybin analog, which is in phase 3 clinical trial to treat major depressive disorder; and HLP004, a deuterated N, N-dimethyltryptamine, which is in phase 2 clinical trial for treating generalized anxiety disorders.

Health Care · Biotechnology: Pharmaceutical Preparations · 100 employees

ALMS vs HELP FAQ

Which is bigger, Alumis or Helus Pharma?

Alumis (ALMS) is larger, with a market capitalization of $926.76M compared with $862.11M for Helus Pharma (HELP).

Which stock has performed better over the past year, ALMS or HELP?

HELP returned +71.25% over the past 12 months, compared with +57.34% for ALMS (price return, excluding dividends). Past performance does not predict future results.

Are Alumis and Helus Pharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons