MetaCap

Ardelyx (ARDX) vs Helus Pharma (HELP)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Helus Pharma (HELP) has outperformed Ardelyx (ARDX) over the past year, gaining 71.2% versus a loss of 35.4%. Over five years, ARDX leads with a +202.8% price change compared with -85.7% for HELP. Ardelyx is the larger company by market cap ($837.8 million vs $813.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ARDX-35.38%HELP+71.25%
+132%+43%-46%
Oct 8, 20251 yearOct 8, 2026
ARDX+161.60%HELP-86.57%
+718%+292%-133%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ARDX versus HELP key metrics
MetricARDXHELP
Share price$3.25$11.13
Market cap$837.82M$813.16M
1-day change-0.76%+3.82%
YTD return-43.91%+31.05%
1-year return-35.38%+71.25%
5-year return+202.78%-85.68%
Forward P/E11.17—
EPS (TTM)$-0.23$-4.15
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$8.40$15.15
52-week low$3.18$3.76
Distance from 52-week high-61.37%-26.53%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+297.53%+257.86%
Average volume4.17M1.77M
Shares outstanding258.19M73.06M
Employees489100
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • HELP has outperformed ARDX by 106.6 percentage points over the past year.

About Ardelyx

ARDX stock →

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 489 employees

About Helus Pharma

HELP stock →

Helus Pharma Inc., doing business as Helus Pharma, operates as a clinical stage pharmaceutical company that focuses on developing therapies to treat psychiatric and neurological conditions. It develops HLP003, a deuterated psilocybin analog, which is in phase 3 clinical trial to treat major depressive disorder; and HLP004, a deuterated N, N-dimethyltryptamine, which is in phase 2 clinical trial for treating generalized anxiety disorders.

Health Care · Biotechnology: Pharmaceutical Preparations · 100 employees

ARDX vs HELP FAQ

Which is bigger, Ardelyx or Helus Pharma?

Ardelyx (ARDX) is larger, with a market capitalization of $837.82M compared with $813.16M for Helus Pharma (HELP).

Which stock has performed better over the past year, ARDX or HELP?

HELP returned +71.25% over the past 12 months, compared with -35.38% for ARDX (price return, excluding dividends). Past performance does not predict future results.

Are Ardelyx and Helus Pharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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