Amneal Pharmaceuticals (AMRX) vs Rhythm Pharmaceuticals (RYTM)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Amneal Pharmaceuticals (AMRX) has outperformed Rhythm Pharmaceuticals (RYTM) over the past year, gaining 89.7% versus a loss of 11.4%. Over five years, RYTM leads with a +682.1% price change compared with +248.4% for AMRX. Amneal Pharmaceuticals is the larger company by market cap ($6.83 billion vs $6.16 billion), about 1.1 times the size, while Rhythm Pharmaceuticals is growing revenue faster (+45.8% vs +8.0%).
Amneal Pharmaceuticals converts more of its revenue into profit, with a net margin of 2.4% versus -103.6%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | AMRX | RYTM |
|---|---|---|
| Share price | $19.60 | $89.47 |
| Market cap | $6.83B | $6.16B |
| 1-day change | -0.25% | +1.15% |
| YTD return | +55.95% | -17.37% |
| 1-year return | +89.67% | -11.40% |
| 5-year return | +248.40% | +682.05% |
| P/E ratio (TTM) | 40.00 | — |
| Forward P/E | 16.44 | — |
| EPS (TTM) | $0.49 | $-3.12 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $3.02B | $189.76M |
| Revenue growth (YoY) | +8.05% | +45.83% |
| Net income (latest FY) | $72.06M | $-196.54M |
| Gross margin | 36.88% | 89.73% |
| Operating margin | 13.05% | -101.19% |
| Net margin | 2.39% | -103.57% |
| 52-week high | $21.18 | $122.20 |
| 52-week low | $9.56 | $74.50 |
| Distance from 52-week high | -7.44% | -26.78% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +15.87% | +54.90% |
| Average volume | 2.26M | 649.06K |
| Shares outstanding | 348.30M | 68.85M |
| Employees | 8,700 | 414 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- AMRX has outperformed RYTM by 101.1 percentage points over the past year.
- Amneal Pharmaceuticals is more profitable, keeping 2.4 cents of every revenue dollar as net income versus -103.6 cents for Rhythm Pharmaceuticals.
- Rhythm Pharmaceuticals grew revenue faster in its latest fiscal year (+45.83% vs +8.05%).
About Amneal Pharmaceuticals
AMRX stock →Amneal Pharmaceuticals, Inc., a global biopharmaceutical company, develops, manufactures, markets, and distributes generics, injectables, biosimilars, and specialty branded pharmaceutical products in the United States, India, Ireland, and internationally. The company operates through three segments: Affordable Medicines, Specialty, and AvKARE.
Health Care · Biotechnology: Pharmaceutical Preparations · 8,700 employees
About Rhythm Pharmaceuticals
RYTM stock →Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity.
Health Care · Biotechnology: Pharmaceutical Preparations · 414 employees
AMRX vs RYTM FAQ
Which is bigger, Amneal Pharmaceuticals or Rhythm Pharmaceuticals?
Amneal Pharmaceuticals (AMRX) is larger, with a market capitalization of $6.83B compared with $6.16B for Rhythm Pharmaceuticals (RYTM).
Which stock has performed better over the past year, AMRX or RYTM?
AMRX returned +89.67% over the past 12 months, compared with -11.40% for RYTM (price return, excluding dividends). Past performance does not predict future results.
Are Amneal Pharmaceuticals and Rhythm Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.