MetaCap

Rhythm Pharmaceuticals Inc. (RYTM)

NASDAQ: RYTMHealthcareBiotechnologyUSD

88.45-2.32 (-2.56%)

At close: Oct 7, 4:00 PM ET · Delayed 15 min

After hours: 88.45 0.00%

RYTM stock chart

Technical analysis

Key statistics

All statistics
EPS (TTM)
-$3.12
52-week range
74.50 – 122.20
Day range
88.23 – 91.37
Volume / Avg
810.74K / 646.31K
Beta
—
Next earnings
Nov 3, 2026

52-week range

$74.50$122.20

RYTM stock today

Shares of Rhythm Pharmaceuticals (RYTM) finished lower on Oct 7 at $88.45, a drop of 2.56% or $2.32 per share, versus the S&P 500's 0.22% decline. At this level, RYTM sits in the middle of its 52-week range of $74.50 to $122.20: 27.6% below the high, set on Dec 11, 2025 and 18.7% above the low. RYTM is down 16.5% year to date, underperforming the S&P 500 (+14.0%). Over the past 12 months, the stock has lost 10.5%.

Rhythm Pharmaceuticals has posted a net loss over the last twelve months (EPS of -$3.12), so its P/E ratio is not meaningful. Rhythm Pharmaceuticals's next earnings report is expected on Nov 3, 2026.

Summary generated from market data by MetaCap's automated system. Methodology

About Rhythm Pharmaceuticals

Company profile

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic obesity, congenital hypothalamic obesity, pro-opiomelanocortin (POMC) and LEPR insufficiency obesities, SRC1 deficiency obesity, and SH2B1 deficiency obesity; and in phase 2 clinical trails for the treatment of Prader-Willi syndrome and MC4R deficiency.

Industry
Biotechnology
CEO
Dr. David P. Meeker M.D.
Headquarters
Boston, MA
Employees
414
IPO year
2017

Financial highlights

Full financials

In fiscal 2025, Rhythm Pharmaceuticals generated $189.8 million in revenue, up 45.8% from fiscal 2024, its 5th consecutive year of revenue growth. Rhythm Pharmaceuticals reported a net loss of $196.5 million, compared with a loss of $260.6 million a year earlier. Gross margin was 89.7% (flat year over year) and operating margin -101.2%.

Rhythm Pharmaceuticals annual revenue, net income and EPS
Fiscal yearFY 2025FY 2024FY 2023FY 2022FY 2021
Revenue$189.76M$130.13M$77.43M$23.64M$3.15M
Growth+45.83%+68.06%+227.56%+649.46%—
Net income$-196.54M$-260.60M$-184.68M$-181.12M$-69.61M
EPS (diluted)$-3.11$-4.34$-3.20$-3.47$-1.40

Analyst forecast

Forecast

Consensus (18 analysts)

none

Avg. price target

$138.59+56.69%

  • Strong buy 5
  • Buy 11
  • Hold 2
  • Sell 0
  • Strong sell 0

Target range

Low $105.00High $160.00

Ratings and targets reflect third-party analyst opinions, not MetaCap recommendations.

Earnings

Earnings history
Next report
Nov 3, 2026
EPS estimate
$-0.68
Last reported (Q2 2026)
Aug 4, 2026
EPS actual vs est.
$-0.73 vs —

Rhythm Pharmaceuticals peers

Healthcare sector
RYTM peer companies
CompanyPrice% ChgMarket capCompare
BLTEBelite Bio Inc ADR156.08+0.30%$6.29Bvs RYTM
IMVTImmunovant Inc.32.04-0.22%$6.62Bvs RYTM
IOVAIovance Biotherapeutics Inc.12.92-0.35%$5.85Bvs RYTM
LGNDLigand Pharmaceuticals Incorporated293.26-1.24%$5.85Bvs RYTM
KODKodiak Sciences Inc91.08-1.36%$5.72Bvs RYTM
CGONCG Oncology Inc.62.38-1.98%$5.53Bvs RYTM
SYRESpyre Therapeutics Inc.80.85+0.92%$7.13Bvs RYTM
PTCTPTC Therapeutics Inc.63.23-0.74%$5.28Bvs RYTM

Indexes, lists and sector

Rhythm Pharmaceuticals stock FAQ

What is Rhythm Pharmaceuticals's stock price today?

RYTM last traded at $88.45 as of Oct 7, 4:00 PM EDT, down 2.56% on the day. Prices are delayed at least 15 minutes.

When is Rhythm Pharmaceuticals's next earnings date?

Rhythm Pharmaceuticals is expected to report earnings on Tuesday, November 3, 2026. Analysts expect EPS of $-0.68.

Who is Rhythm Pharmaceuticals's CEO?

Dr. David P. Meeker M.D. is the chief executive officer of Rhythm Pharmaceuticals Inc., which has about 414 employees.

What is the RYTM 52-week high?

The 52-week high for RYTM is $122.20 and the 52-week low is $74.50. The stock is currently 27.6% below its high.

Compare RYTM