MetaCap

AnaptysBio (ANAB) vs Nektar Therapeutics (NKTR)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

AnaptysBio (ANAB) has outperformed Nektar Therapeutics (NKTR) over the past year, gaining 117.8% versus a loss of 27.9%. Over five years, ANAB leads with a +141.8% price change compared with -84.3% for NKTR. Nektar Therapeutics is the larger company by market cap ($1.39 billion vs $1.38 billion), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANAB+117.77%NKTR-27.86%
+242%+96%-51%
Oct 8, 20251 yearOct 8, 2026
ANAB+147.29%NKTR-84.02%
+289%+87%-116%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANAB versus NKTR key metrics
MetricANABNKTR
Share price$46.21$40.80
Market cap$1.38B$1.39B
1-day change+1.23%+1.34%
YTD return+42.98%-3.50%
1-year return+117.77%-27.86%
5-year return+141.77%-84.29%
Forward P/E9.12—
EPS (TTM)$-0.96$-18.96
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$72.36$109.00
52-week low$20.18$33.40
Distance from 52-week high-36.14%-62.57%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+88.81%+246.57%
Average volume563.32K1.07M
Shares outstanding29.90M34.14M
Employees—63
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ANAB has outperformed NKTR by 145.6 percentage points over the past year.

About AnaptysBio

ANAB stock →

AnaptysBio, Inc. discovers and out-licenses therapeutic bodies in the United States.

Health Care · Biotechnology: Pharmaceutical Preparations

About Nektar Therapeutics

NKTR stock →

Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing medicines in the field of immunotherapy in the United States and internationally. It develops rezpegaldesleukin, which is in Phase 2b to treat underlying immune system imbalance in people with autoimmune disorders and inflammatory diseases; NKTR-0165 to treat ulcerative colitis, vitiligo, and multiple sclerosis; NKTR-0166 to treat autoimmune disease; NKTR-422 to treat fibrotic diseases; and NKTR-255 to treat solid tumors and large b-cell lymphoma.

Health Care · Biotechnology: Pharmaceutical Preparations · 63 employees

ANAB vs NKTR FAQ

Which is bigger, AnaptysBio or Nektar Therapeutics?

Nektar Therapeutics (NKTR) is larger, with a market capitalization of $1.39B compared with $1.38B for AnaptysBio (ANAB).

Which stock has performed better over the past year, ANAB or NKTR?

ANAB returned +117.77% over the past 12 months, compared with -27.86% for NKTR (price return, excluding dividends). Past performance does not predict future results.

Are AnaptysBio and Nektar Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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