Nektar Therapeutics (NKTR) vs Tyra Biosciences (TYRA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Tyra Biosciences (TYRA) has outperformed Nektar Therapeutics (NKTR) over the past year, gaining 46.5% versus a loss of 30.6%. Over five years, TYRA leads with a +22.2% price change compared with -84.5% for NKTR. Nektar Therapeutics is the larger company by market cap ($1.39 billion vs $1.37 billion), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | NKTR | TYRA |
|---|---|---|
| Share price | $40.80 | $19.97 |
| Market cap | $1.39B | $1.37B |
| 1-day change | +1.34% | -2.06% |
| YTD return | -4.78% | -24.04% |
| 1-year return | -30.59% | +46.52% |
| 5-year return | -84.49% | +22.22% |
| EPS (TTM) | $-18.96 | $-2.39 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $109.00 | $40.65 |
| 52-week low | $33.40 | $13.29 |
| Distance from 52-week high | -62.57% | -50.87% |
| Analyst consensus | strong_buy | strong_buy |
| Avg. price target upside | +246.57% | +137.61% |
| Average volume | 1.07M | 857.13K |
| Shares outstanding | 34.14M | 68.76M |
| Employees | 63 | 87 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TYRA has outperformed NKTR by 77.1 percentage points over the past year.
About Nektar Therapeutics
NKTR stock →Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing medicines in the field of immunotherapy in the United States and internationally. It develops rezpegaldesleukin, which is in Phase 2b to treat underlying immune system imbalance in people with autoimmune disorders and inflammatory diseases; NKTR-0165 to treat ulcerative colitis, vitiligo, and multiple sclerosis; NKTR-0166 to treat autoimmune disease; NKTR-422 to treat fibrotic diseases; and NKTR-255 to treat solid tumors and large b-cell lymphoma.
Health Care · Biotechnology: Pharmaceutical Preparations · 63 employees
About Tyra Biosciences
TYRA stock →Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions.
Health Care · Biotechnology: Pharmaceutical Preparations · 87 employees
NKTR vs TYRA FAQ
Which is bigger, Nektar Therapeutics or Tyra Biosciences?
Nektar Therapeutics (NKTR) is larger, with a market capitalization of $1.39B compared with $1.37B for Tyra Biosciences (TYRA).
Which stock has performed better over the past year, NKTR or TYRA?
TYRA returned +46.52% over the past 12 months, compared with -30.59% for NKTR (price return, excluding dividends). Past performance does not predict future results.
Are Nektar Therapeutics and Tyra Biosciences in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.