Annexon (ANNX) vs Helus Pharma (HELP)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
Helus Pharma (HELP) has outperformed Annexon (ANNX) over the past year, gaining 73.1% versus a gain of 30.6%. Over five years, ANNX leads with a -81.8% price change compared with -86.0% for HELP. Helus Pharma is the larger company by market cap ($767.9 million vs $760.2 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANNX | HELP |
|---|---|---|
| Share price | $4.01 | $10.51 |
| Market cap | $760.21M | $767.86M |
| 1-day change | -0.50% | -2.32% |
| YTD return | -20.12% | +28.48% |
| 1-year return | +30.62% | +73.15% |
| 5-year return | -81.77% | -85.96% |
| EPS (TTM) | $-1.13 | $-4.15 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $7.18 | $15.15 |
| 52-week low | $2.54 | $3.76 |
| Distance from 52-week high | -44.15% | -30.63% |
| Average volume | 3.19M | 1.79M |
| Shares outstanding | 189.58M | 73.06M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- HELP has outperformed ANNX by 42.5 percentage points over the past year.
ANNX vs HELP FAQ
Which is bigger, Annexon or Helus Pharma?
Helus Pharma (HELP) is larger, with a market capitalization of $767.86M compared with $760.21M for Annexon (ANNX).
Which stock has performed better over the past year, ANNX or HELP?
HELP returned +73.15% over the past 12 months, compared with +30.62% for ANNX (price return, excluding dividends). Past performance does not predict future results.
Are Annexon and Helus Pharma in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.