Annexon (ANNX) vs Lexicon Pharmaceuticals (LXRX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
Annexon (ANNX) has outperformed Lexicon Pharmaceuticals (LXRX) over the past year, gaining 30.6% versus a gain of 15.8%. Over five years, LXRX leads with a -71.4% price change compared with -81.8% for ANNX. Lexicon Pharmaceuticals is the larger company by market cap ($783.1 million vs $760.2 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANNX | LXRX |
|---|---|---|
| Share price | $4.01 | $1.76 |
| Market cap | $760.21M | $783.12M |
| 1-day change | -0.50% | +0.57% |
| YTD return | -20.12% | +53.04% |
| 1-year return | +30.62% | +15.79% |
| 5-year return | -81.77% | -71.43% |
| EPS (TTM) | $-1.13 | $-0.16 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $7.18 | $2.68 |
| 52-week low | $2.54 | $1.10 |
| Distance from 52-week high | -44.15% | -34.33% |
| Average volume | 3.19M | 2.91M |
| Shares outstanding | 189.58M | 444.96M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ANNX has outperformed LXRX by 14.8 percentage points over the past year.
ANNX vs LXRX FAQ
Which is bigger, Annexon or Lexicon Pharmaceuticals?
Lexicon Pharmaceuticals (LXRX) is larger, with a market capitalization of $783.12M compared with $760.21M for Annexon (ANNX).
Which stock has performed better over the past year, ANNX or LXRX?
ANNX returned +30.62% over the past 12 months, compared with +15.79% for LXRX (price return, excluding dividends). Past performance does not predict future results.
Are Annexon and Lexicon Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.