MetaCap

Helus Pharma (HELP) vs Lexicon Pharmaceuticals (LXRX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

Helus Pharma (HELP) has outperformed Lexicon Pharmaceuticals (LXRX) over the past year, gaining 73.1% versus a gain of 15.8%. Over five years, LXRX leads with a -71.4% price change compared with -86.0% for HELP. Lexicon Pharmaceuticals is the larger company by market cap ($783.1 million vs $767.9 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

HELP+63.45%LXRX+13.55%
+126%+39%-48%
Oct 6, 20251 yearOct 7, 2026
HELP-86.83%LXRX-68.40%
+16%-42%-100%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

HELP versus LXRX key metrics
MetricHELPLXRX
Share price$10.51$1.76
Market cap$767.86M$783.12M
1-day change-2.32%+0.57%
YTD return+28.48%+53.04%
1-year return+73.15%+15.79%
5-year return-85.96%-71.43%
EPS (TTM)$-4.15$-0.16
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$15.15$2.68
52-week low$3.76$1.10
Distance from 52-week high-30.63%-34.33%
Average volume1.79M2.91M
Shares outstanding73.06M444.96M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • HELP has outperformed LXRX by 57.4 percentage points over the past year.

HELP vs LXRX FAQ

Which is bigger, Helus Pharma or Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals (LXRX) is larger, with a market capitalization of $783.12M compared with $767.86M for Helus Pharma (HELP).

Which stock has performed better over the past year, HELP or LXRX?

HELP returned +73.15% over the past 12 months, compared with +15.79% for LXRX (price return, excluding dividends). Past performance does not predict future results.

Are Helus Pharma and Lexicon Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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