MetaCap

Alto Neuroscience (ANRO) vs OPKO Health (OPK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Alto Neuroscience (ANRO) has outperformed OPKO Health (OPK) over the past year, gaining 304.8% versus a loss of 11.5%. OPKO Health is the larger company by market cap ($1.03 billion vs $956.3 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANRO+292.43%OPK-10.97%
+516%+230%-55%
Oct 8, 20251 yearOct 9, 2026
ANRO+17.73%OPK+38.00%
+99%-1%-100%
Jan 29, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANRO versus OPK key metrics
MetricANROOPK
Share price$24.37$1.38
Market cap$956.33M$1.03B
1-day change+1.41%+0.73%
YTD return+36.91%+9.52%
1-year return+304.82%-11.54%
5-year return—-62.90%
EPS (TTM)$-2.31$-0.09
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$37.48$1.75
52-week low$5.23$0.98
Distance from 52-week high-34.98%-21.14%
Analyst consensusstrong_buynone
Avg. price target upside+57.49%+217.39%
Average volume538.53K3.35M
Shares outstanding39.24M746.33M
Employees682,275
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ANRO has outperformed OPK by 316.4 percentage points over the past year.

About Alto Neuroscience

ANRO stock →

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States.

Health Care · Biotechnology: Pharmaceutical Preparations · 68 employees

About OPKO Health

OPK stock →

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 2,275 employees

ANRO vs OPK FAQ

Which is bigger, Alto Neuroscience or OPKO Health?

OPKO Health (OPK) is larger, with a market capitalization of $1.03B compared with $956.33M for Alto Neuroscience (ANRO).

Which stock has performed better over the past year, ANRO or OPK?

ANRO returned +304.82% over the past 12 months, compared with -11.54% for OPK (price return, excluding dividends). Past performance does not predict future results.

Are Alto Neuroscience and OPKO Health in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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