MetaCap

AN2 Therapeutics (ANTX) vs PepGen (PEPG)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

AN2 Therapeutics (ANTX) has outperformed PepGen (PEPG) over the past year, gaining 262.8% versus a loss of 51.1%. AN2 Therapeutics is the larger company by market cap ($176.6 million vs $164.6 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANTX+262.79%PEPG-51.13%
+410%+157%-95%
Oct 8, 20251 yearOct 8, 2026
ANTX-75.13%PEPG-81.38%
+51%-25%-102%
May 2, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANTX versus PEPG key metrics
MetricANTXPEPG
Share price$4.68$2.38
Market cap$176.61M$164.62M
1-day change-3.51%-0.83%
YTD return+310.53%-63.44%
1-year return+262.79%-51.13%
EPS (TTM)$-1.05$-1.01
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.19$7.80
52-week low$1.00$1.31
Distance from 52-week high-34.91%-69.49%
Analyst consensusnonenone
Avg. price target upside+92.31%+328.15%
Average volume235.07K971.65K
Shares outstanding37.74M69.17M
Employees2157
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ANTX has outperformed PEPG by 313.9 percentage points over the past year.

About AN2 Therapeutics

ANTX stock →

AN2 Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics. The company's initial candidate includes epetraborole, which is phase 3 clinical trial as a once-daily oral treatment for patients with non-tuberculous mycobacterial lung disease, as well as studying for the treatment of acute melioidosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees

About PepGen

PEPG stock →

PepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neurologic diseases in the United States. The company engages in the development of PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 2 clinical trial for the treatment of myotonic dystrophy type 1; and FREEDOM2-DM1, which is in Phase 2 for the treatment of myotonic dystrophy type 1.

Health Care · Biotechnology: Pharmaceutical Preparations · 57 employees

ANTX vs PEPG FAQ

Which is bigger, AN2 Therapeutics or PepGen?

AN2 Therapeutics (ANTX) is larger, with a market capitalization of $176.61M compared with $164.62M for PepGen (PEPG).

Which stock has performed better over the past year, ANTX or PEPG?

ANTX returned +262.79% over the past 12 months, compared with -51.13% for PEPG (price return, excluding dividends). Past performance does not predict future results.

Are AN2 Therapeutics and PepGen in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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