MetaCap

Ardelyx (ARDX) vs Janux Therapeutics (JANX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Janux Therapeutics (JANX) has outperformed Ardelyx (ARDX) over the past year, losing 23.6% versus a loss of 35.4%. Over five years, ARDX leads with a +202.8% price change compared with -12.4% for JANX. Janux Therapeutics is the larger company by market cap ($1.15 billion vs $837.8 million), about 1.4 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ARDX-35.38%JANX-23.55%
+63%+4%-55%
Oct 8, 20251 yearOct 8, 2026
ARDX+161.60%JANX-13.19%
+717%+304%-109%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ARDX versus JANX key metrics
MetricARDXJANX
Share price$3.25$18.76
Market cap$837.82M$1.15B
1-day change-0.76%+1.41%
YTD return-43.91%+34.06%
1-year return-35.38%-23.55%
5-year return+202.78%-12.45%
Forward P/E11.17—
EPS (TTM)$-0.23$-1.64
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$8.40$35.34
52-week low$3.18$12.12
Distance from 52-week high-61.37%-46.92%
Analyst consensusstrong_buynone
Avg. price target upside+297.53%+93.18%
Average volume4.17M845.95K
Shares outstanding258.19M61.14M
Employees489113
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • JANX has outperformed ARDX by 11.8 percentage points over the past year.

About Ardelyx

ARDX stock →

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 489 employees

About Janux Therapeutics

JANX stock →

Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engager (TRACTr), Tumor Activated Immunomodulator (TRACIr), and Adaptive Immune Response Modulator (ARM) platforms technology to treat patients with cancer. The company's clinical candidates include JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor that is in Phase 1 clinical trial for the treatment of various solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, renal cell carcinoma, small cell lung cancer, pancreatic ductal adenocarcinoma, and triple-negative breast cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 113 employees

ARDX vs JANX FAQ

Which is bigger, Ardelyx or Janux Therapeutics?

Janux Therapeutics (JANX) is larger, with a market capitalization of $1.15B compared with $837.82M for Ardelyx (ARDX).

Which stock has performed better over the past year, ARDX or JANX?

JANX returned -23.55% over the past 12 months, compared with -35.38% for ARDX (price return, excluding dividends). Past performance does not predict future results.

Are Ardelyx and Janux Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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