MetaCap

Arrowhead Pharmaceuticals (ARWR) vs Cytokinetics (CYTK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Arrowhead Pharmaceuticals (ARWR) has outperformed Cytokinetics (CYTK) over the past year, gaining 68.3% versus a gain of 1.6%. Over five years, CYTK leads with a +65.7% price change compared with -7.1% for ARWR. Arrowhead Pharmaceuticals is the larger company by market cap ($8.68 billion vs $8.50 billion), about 1.0 times the size.

Arrowhead Pharmaceuticals converts more of its revenue into profit, with a net margin of -0.2% versus -891.6%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ARWR+68.25%CYTK+1.58%
+153%+68%-17%
Oct 7, 20251 yearOct 7, 2026
ARWR+1.91%CYTK+60.80%
+158%+32%-94%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ARWR versus CYTK key metrics
MetricARWRCYTK
Share price$61.48$61.12
Market cap$8.68B$8.50B
1-day change-0.10%-0.37%
YTD return-7.40%-3.81%
1-year return+68.25%+1.58%
5-year return-7.07%+65.68%
EPS (TTM)$-2.28$-7.22
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$829.45M$88.04M
Revenue growth (YoY)+23258.15%+376.56%
Net income (latest FY)$-1.63M$-784.96M
Operating margin11.86%-695.44%
Net margin-0.20%-891.60%
52-week high$95.49$88.31
52-week low$34.61$54.30
Distance from 52-week high-35.62%-30.79%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+74.41%+79.81%
Average volume1.90M1.96M
Shares outstanding141.25M139.02M
Employees711673
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ARWR has outperformed CYTK by 66.7 percentage points over the past year.
  • Arrowhead Pharmaceuticals is more profitable, keeping -0.2 cents of every revenue dollar as net income versus -891.6 cents for Cytokinetics.
  • Arrowhead Pharmaceuticals grew revenue faster in its latest fiscal year (+23258.15% vs +376.56%).

About Arrowhead Pharmaceuticals

ARWR stock →

Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States.

Health Care · Biotechnology: Pharmaceutical Preparations · 711 employees

About Cytokinetics

CYTK stock →

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM.

Health Care · Biotechnology: Pharmaceutical Preparations · 673 employees

ARWR vs CYTK FAQ

Which is bigger, Arrowhead Pharmaceuticals or Cytokinetics?

Arrowhead Pharmaceuticals (ARWR) is larger, with a market capitalization of $8.68B compared with $8.50B for Cytokinetics (CYTK).

Which stock has performed better over the past year, ARWR or CYTK?

ARWR returned +68.25% over the past 12 months, compared with +1.58% for CYTK (price return, excluding dividends). Past performance does not predict future results.

Are Arrowhead Pharmaceuticals and Cytokinetics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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