Arrowhead Pharmaceuticals (ARWR) vs Praxis Precision Medicines (PRAX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Praxis Precision Medicines (PRAX) has outperformed Arrowhead Pharmaceuticals (ARWR) over the past year, gaining 434.2% versus a gain of 68.3%. Over five years, ARWR leads with a -7.1% price change compared with -7.4% for PRAX. Arrowhead Pharmaceuticals is the larger company by market cap ($8.58 billion vs $7.36 billion), about 1.2 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ARWR | PRAX |
|---|---|---|
| Share price | $60.74 | $263.55 |
| Market cap | $8.58B | $7.36B |
| 1-day change | -1.20% | -5.20% |
| YTD return | -7.40% | -5.67% |
| 1-year return | +68.25% | +434.24% |
| 5-year return | -7.07% | -7.37% |
| EPS (TTM) | $-2.28 | $-12.95 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $829.45M | $0 |
| Revenue growth (YoY) | +23258.15% | -100.00% |
| Net income (latest FY) | $-1.63M | $-303.27M |
| Operating margin | 11.86% | — |
| Net margin | -0.20% | — |
| 52-week high | $95.49 | $392.70 |
| 52-week low | $34.61 | $50.56 |
| Distance from 52-week high | -36.39% | -32.89% |
| Analyst consensus | strong_buy | strong_buy |
| Avg. price target upside | +76.54% | +144.52% |
| Average volume | 1.90M | 403.18K |
| Shares outstanding | 141.25M | 27.92M |
| Employees | 711 | 168 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PRAX has outperformed ARWR by 366.0 percentage points over the past year.
- Arrowhead Pharmaceuticals grew revenue faster in its latest fiscal year (+23258.15% vs -100.00%).
About Arrowhead Pharmaceuticals
ARWR stock →Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States.
Health Care · Biotechnology: Pharmaceutical Preparations · 711 employees
About Praxis Precision Medicines
PRAX stock →Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide.
Health Care · Biotechnology: Pharmaceutical Preparations · 168 employees
ARWR vs PRAX FAQ
Which is bigger, Arrowhead Pharmaceuticals or Praxis Precision Medicines?
Arrowhead Pharmaceuticals (ARWR) is larger, with a market capitalization of $8.58B compared with $7.36B for Praxis Precision Medicines (PRAX).
Which stock has performed better over the past year, ARWR or PRAX?
PRAX returned +434.24% over the past 12 months, compared with +68.25% for ARWR (price return, excluding dividends). Past performance does not predict future results.
Are Arrowhead Pharmaceuticals and Praxis Precision Medicines in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.