MetaCap

Assembly Biosciences (ASMB) vs Crescent Biopharma (CBIO)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Crescent Biopharma (CBIO) has outperformed Assembly Biosciences (ASMB) over the past year, gaining 19.5% versus a loss of 3.8%. Over five years, ASMB leads with a -41.3% price change compared with -93.2% for CBIO. Crescent Biopharma is the larger company by market cap ($496.7 million vs $449.6 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ASMB-3.81%CBIO+19.49%
+147%+59%-29%
Oct 7, 20251 yearOct 7, 2026
ASMB-41.87%CBIO-92.94%
+91%-7%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ASMB versus CBIO key metrics
MetricASMBCBIO
Share price$22.08$13.37
Market cap$449.56M$496.65M
1-day change-3.79%-0.89%
YTD return-32.52%+13.74%
1-year return-3.81%+19.49%
5-year return-41.33%-93.19%
P/E ratio (TTM)21.23—
EPS (TTM)$1.04$-7.63
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$39.71$27.41
52-week low$21.80$8.72
Distance from 52-week high-44.40%-51.22%
Analyst consensusnonestrong_buy
Avg. price target upside+135.51%+135.60%
Average volume278.07K397.58K
Shares outstanding20.36M37.14M
Employees7369
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • CBIO has outperformed ASMB by 23.3 percentage points over the past year.

About Assembly Biosciences

ASMB stock →

Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide. Its pipeline includes long-acting helicase-primase inhibitors candidates, including ABI-5366 and ABI-1179, which are in Phase 1 clinical studies for recurrent genital herpes; and ABI-6250, an orally bioavailable hepatitis delta virus entry inhibitor that is in Phase 1a clinical study for the treatment of chronic hepatitis delta virus (HDV) infection.

Health Care · Biotechnology: Pharmaceutical Preparations · 73 employees

About Crescent Biopharma

CBIO stock →

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003.

Health Care · Biotechnology: Pharmaceutical Preparations · 69 employees

ASMB vs CBIO FAQ

Which is bigger, Assembly Biosciences or Crescent Biopharma?

Crescent Biopharma (CBIO) is larger, with a market capitalization of $496.65M compared with $449.56M for Assembly Biosciences (ASMB).

Which stock has performed better over the past year, ASMB or CBIO?

CBIO returned +19.49% over the past 12 months, compared with -3.81% for ASMB (price return, excluding dividends). Past performance does not predict future results.

Are Assembly Biosciences and Crescent Biopharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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