aTyr Pharma (ATYR) vs Dyadic International (DYAI)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Dyadic International (DYAI) has outperformed aTyr Pharma (ATYR) over the past year, losing 60.7% versus a loss of 74.2%. Over five years, DYAI leads with a -90.8% price change compared with -97.2% for ATYR. aTyr Pharma is the larger company by market cap ($24.1 million vs $17.8 million), about 1.4 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ATYR | DYAI |
|---|---|---|
| Share price | $0.2462 | $0.4441 |
| Market cap | $24.15M | $17.79M |
| 1-day change | -3.56% | -0.07% |
| YTD return | -68.56% | -52.72% |
| 1-year return | -74.17% | -60.67% |
| 5-year return | -97.17% | -90.84% |
| EPS (TTM) | $-0.62 | $-0.23 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.12 | $1.60 |
| 52-week low | $0.246 | $0.34 |
| Distance from 52-week high | -78.02% | -72.24% |
| Analyst consensus | buy | none |
| Avg. price target upside | +1061.66% | +1138.46% |
| Average volume | 3.24M | 201.91K |
| Shares outstanding | 98.09M | 40.06M |
| Employees | 58 | 5 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Biological Products (No Diagnostic Substances) | Biotechnology: Biological Products (No Diagnostic Substances) |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- DYAI has outperformed ATYR by 13.5 percentage points over the past year.
About aTyr Pharma
ATYR stock →aTyr Pharma, Inc., a clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States. Its lead therapeutic candidate efzofitimod, a selective modulator of NRP2 that is in Phase 3 clinical trial for the treatment of pulmonary sarcoidosis; Phase 2 clinical trial to treat Sarcoidosis and systemic sclerosis- interstitial lung disease (ILDs); and treatment of other ILDs, such as chronic hypersensitivity pneumonitis (CHP) and connective tissue disease related ILD.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 58 employees
About Dyadic International
DYAI stock →Dyadic International, Inc., together with its subsidiaries, a biotechnology platform company, develops, manufactures, and commercializes proteins and enzymes in the United States. The company offers Dapibus Protein Production Platform, a proprietary expression system designed to produce non-animal proteins and enzymes for non-pharmaceutical markets, including life sciences, food and nutrition, and bio-industrial sector; and C1 Protein Production Platform, a thermophilic fungal platform for large-scale production of proteins.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 5 employees
ATYR vs DYAI FAQ
Which is bigger, aTyr Pharma or Dyadic International?
aTyr Pharma (ATYR) is larger, with a market capitalization of $24.15M compared with $17.79M for Dyadic International (DYAI).
Which stock has performed better over the past year, ATYR or DYAI?
DYAI returned -60.67% over the past 12 months, compared with -74.17% for ATYR (price return, excluding dividends). Past performance does not predict future results.
Are aTyr Pharma and Dyadic International in the same industry?
Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.