MetaCap

Avalo Therapeutics (AVTX) vs Collegium Pharmaceutical (COLL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

Avalo Therapeutics (AVTX) has outperformed Collegium Pharmaceutical (COLL) over the past year, gaining 0.7% versus a loss of 34.3%. Over five years, COLL leads with a +4.5% price change compared with -99.8% for AVTX. Avalo Therapeutics is the larger company by market cap ($728.3 million vs $713.9 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AVTX+0.74%COLL-34.32%
+75%+18%-40%
Oct 7, 20251 yearOct 7, 2026
AVTX-99.78%COLL+8.08%
+158%+23%-112%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AVTX versus COLL key metrics
MetricAVTXCOLL
Share price$13.58$21.93
Market cap$728.30M$713.94M
1-day change-0.07%+0.23%
YTD return-25.22%-52.63%
1-year return+0.74%-34.32%
5-year return-99.79%+4.53%
P/E ratio (TTM)—17.27
Forward P/E—3.30
EPS (TTM)$-4.31$1.27
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$24.27$50.79
52-week low$12.51$21.43
Distance from 52-week high-44.05%-56.82%
Average volume929.44K747.73K
Shares outstanding53.63M32.56M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AVTX has outperformed COLL by 35.1 percentage points over the past year.

AVTX vs COLL FAQ

Which is bigger, Avalo Therapeutics or Collegium Pharmaceutical?

Avalo Therapeutics (AVTX) is larger, with a market capitalization of $728.30M compared with $713.94M for Collegium Pharmaceutical (COLL).

Which stock has performed better over the past year, AVTX or COLL?

AVTX returned +0.74% over the past 12 months, compared with -34.32% for COLL (price return, excluding dividends). Past performance does not predict future results.

Are Avalo Therapeutics and Collegium Pharmaceutical in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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