Collegium Pharmaceutical (COLL) vs Wave Life Sciences (WVE)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
Collegium Pharmaceutical (COLL) has outperformed Wave Life Sciences (WVE) over the past year, losing 34.3% versus a loss of 50.8%. Over five years, COLL leads with a +4.5% price change compared with -31.3% for WVE. Collegium Pharmaceutical is the larger company by market cap ($713.9 million vs $697.6 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | COLL | WVE |
|---|---|---|
| Share price | $21.93 | $3.54 |
| Market cap | $713.94M | $697.55M |
| 1-day change | +0.23% | +0.57% |
| YTD return | -52.63% | -79.18% |
| 1-year return | -34.32% | -50.76% |
| 5-year return | +4.53% | -31.26% |
| P/E ratio (TTM) | 17.27 | — |
| Forward P/E | 3.30 | — |
| EPS (TTM) | $1.27 | $-1.08 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $50.79 | $21.73 |
| 52-week low | $21.43 | $3.43 |
| Distance from 52-week high | -56.82% | -83.71% |
| Average volume | 747.73K | 3.10M |
| Shares outstanding | 32.56M | 197.05M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- COLL has outperformed WVE by 16.4 percentage points over the past year.
COLL vs WVE FAQ
Which is bigger, Collegium Pharmaceutical or Wave Life Sciences?
Collegium Pharmaceutical (COLL) is larger, with a market capitalization of $713.94M compared with $697.55M for Wave Life Sciences (WVE).
Which stock has performed better over the past year, COLL or WVE?
COLL returned -34.32% over the past 12 months, compared with -50.76% for WVE (price return, excluding dividends). Past performance does not predict future results.
Are Collegium Pharmaceutical and Wave Life Sciences in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.