MetaCap

Axogen (AXGN) vs TransMedics Group (TMDX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Axogen (AXGN) has outperformed TransMedics Group (TMDX) over the past year, gaining 113.3% versus a loss of 29.6%. Over five years, TMDX leads with a +205.3% price change compared with +164.6% for AXGN. TransMedics Group is the larger company by market cap ($2.74 billion vs $2.12 billion), about 1.3 times the size.

On valuation, TransMedics Group trades at a lower forward P/E (35.0x vs 52.6x for Axogen).

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AXGN+113.25%TMDX-29.61%
+219%+80%-59%
Oct 7, 20251 yearOct 7, 2026
AXGN+152.20%TMDX+195.88%
+572%+234%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AXGN versus TMDX key metrics
MetricAXGNTMDX
Share price$36.18$79.00
Market cap$2.12B$2.74B
1-day change+0.39%-2.55%
YTD return+10.11%-33.36%
1-year return+113.25%-29.61%
5-year return+164.61%+205.35%
P/E ratio (TTM)—20.47
Forward P/E52.5935.05
EPS (TTM)$-0.67$3.86
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$605.49M
Revenue growth (YoY)—+37.13%
Net income (latest FY)—$190.29M
Gross margin—59.92%
Operating margin—17.93%
Net margin—31.43%
52-week high$52.91$156.00
52-week low$15.27$60.11
Distance from 52-week high-31.62%-49.36%
Analyst consensusstrong_buybuy
Avg. price target upside+48.76%+26.35%
Average volume1.23M815.54K
Shares outstanding58.67M34.68M
Employees622898
SectorHealth CareHealth Care
IndustryBiotechnology: Electromedical & Electrotherapeutic ApparatusBiotechnology: Electromedical & Electrotherapeutic Apparatus

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AXGN has outperformed TMDX by 142.9 percentage points over the past year.

About Axogen

AXGN stock →

Axogen, Inc., together with its subsidiaries, engages in the development and commercialization of the technologies used for peripheral nerve regeneration and repair worldwide. The company offers Avance Nerve Graft, a processed nerve allograft intended for the surgical repair of peripheral nerve discontinuities; Axoguard Nerve Connector, a coaptation aid used to align and connect severed peripheral nerve ends in a tensionless repair; and Axoguard Nerve Protector, a product used to protect and wrap damaged peripheral nerves and reinforce reconstructed nerve gaps.

Health Care · Biotechnology: Electromedical & Electrotherapeutic Apparatus · 622 employees

About TransMedics Group

TMDX stock →

TransMedics Group, Inc., a commercial-stage medical technology company, engages in transforming organ transplant therapy for end-stage organ failure patients in the United States and internationally. The company provides Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system that utilizes its proprietary and customized technology to replicate near-physiologic conditions for donor organs outside of the human body.

Health Care · Biotechnology: Electromedical & Electrotherapeutic Apparatus · 898 employees

AXGN vs TMDX FAQ

Which is bigger, Axogen or TransMedics Group?

TransMedics Group (TMDX) is larger, with a market capitalization of $2.74B compared with $2.12B for Axogen (AXGN).

Which stock has performed better over the past year, AXGN or TMDX?

AXGN returned +113.25% over the past 12 months, compared with -29.61% for TMDX (price return, excluding dividends). Past performance does not predict future results.

Are Axogen and TransMedics Group in the same industry?

Yes. Both are classified in the Biotechnology: Electromedical & Electrotherapeutic Apparatus industry within the Health Care sector.

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