Stryker (SYK) vs TransMedics Group (TMDX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Stryker (SYK) has outperformed TransMedics Group (TMDX) over the past year, losing 26.2% versus a loss of 33.1%. Over five years, TMDX leads with a +197.6% price change compared with +4.0% for SYK. Stryker is the larger company by market cap ($106.98 billion vs $2.74 billion), about 39.0 times the size, while TransMedics Group is growing revenue faster (+37.1% vs +11.2%).
On valuation, Stryker trades at a lower forward P/E (16.7x vs 35.1x for TransMedics Group). Stryker pays a dividend yielding 1.25%, while TransMedics Group does not currently pay one. TransMedics Group converts more of its revenue into profit, with a net margin of 31.4% versus 12.9%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | SYK | TMDX |
|---|---|---|
| Share price | $278.91 | $79.06 |
| Market cap | $106.98B | $2.74B |
| 1-day change | +0.70% | +0.08% |
| YTD return | -21.20% | -35.06% |
| 1-year return | -26.20% | -33.08% |
| 5-year return | +4.00% | +197.55% |
| P/E ratio (TTM) | 28.90 | 20.48 |
| Forward P/E | 16.70 | 35.07 |
| EPS (TTM) | $9.65 | $3.86 |
| Dividend yield | 1.25% | 0.00% |
| Annual dividend | $3.48 | $0.00 |
| Revenue (latest FY) | $25.12B | $605.49M |
| Revenue growth (YoY) | +11.16% | +37.13% |
| Net income (latest FY) | $3.25B | $190.29M |
| Gross margin | 63.96% | 59.92% |
| Operating margin | 19.47% | 17.93% |
| Net margin | 12.92% | 31.43% |
| 52-week high | $392.55 | $156.00 |
| 52-week low | $267.00 | $60.11 |
| Distance from 52-week high | -28.95% | -49.32% |
| Analyst consensus | buy | buy |
| Avg. price target upside | +31.28% | +26.26% |
| Average volume | 2.64M | 820.41K |
| Shares outstanding | 383.57M | 34.68M |
| Employees | 56,000 | 898 |
| Sector | Health Care | Health Care |
| Industry | Medical/Dental Instruments | Biotechnology: Electromedical & Electrotherapeutic Apparatus |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Stryker is about 39.0 times larger than TransMedics Group by market value ($106.98B vs $2.74B).
- Stryker trades at a higher earnings multiple (28.9x vs 20.5x trailing P/E).
- Stryker offers a meaningfully higher dividend yield (1.25% vs 0.00%).
- TransMedics Group is more profitable, keeping 31.4 cents of every revenue dollar as net income versus 12.9 cents for Stryker.
- TransMedics Group grew revenue faster in its latest fiscal year (+37.13% vs +11.16%).
About Stryker
SYK stock →Stryker Corporation operates as a medical technology company in the United States and internationally. It operates through two segments, MedSurg and Neurotechnology, and Orthopaedics.
Health Care · Medical/Dental Instruments · 56,000 employees
About TransMedics Group
TMDX stock →TransMedics Group, Inc., a commercial-stage medical technology company, engages in transforming organ transplant therapy for end-stage organ failure patients in the United States and internationally. The company provides Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system that utilizes its proprietary and customized technology to replicate near-physiologic conditions for donor organs outside of the human body.
Health Care · Biotechnology: Electromedical & Electrotherapeutic Apparatus · 898 employees
SYK vs TMDX FAQ
Which is bigger, Stryker or TransMedics Group?
Stryker (SYK) is larger, with a market capitalization of $106.98B compared with $2.74B for TransMedics Group (TMDX).
Which stock has performed better over the past year, SYK or TMDX?
SYK returned -26.20% over the past 12 months, compared with -33.08% for TMDX (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, SYK or TMDX?
TMDX has the lower trailing P/E at 20.5, versus 28.9 for SYK. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Which pays a higher dividend, Stryker or TransMedics Group?
Stryker pays a dividend yielding 1.25%, while TransMedics Group does not currently pay a regular dividend.
Are Stryker and TransMedics Group in the same industry?
Both are in the Health Care sector, but in different industries: Medical/Dental Instruments for Stryker and Biotechnology: Electromedical & Electrotherapeutic Apparatus for TransMedics Group.