MetaCap

Aytu BioPharma (AYTU) vs Shuttle Pharmaceuticals (SHPH)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Aytu BioPharma (AYTU) has outperformed Shuttle Pharmaceuticals (SHPH) over the past year, losing 13.1% versus a loss of 88.8%. Shuttle Pharmaceuticals is the larger company by market cap ($26.4 million vs $22.3 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AYTU-13.14%SHPH-88.79%
+29%-35%-99%
Oct 7, 20251 yearOct 7, 2026
AYTU-55.43%SHPH-99.98%
+173%+30%-113%
Aug 29, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AYTU versus SHPH key metrics
MetricAYTUSHPH
Share price$2.05$5.55
Market cap$22.28M$26.44M
1-day change0.00%+17.83%
YTD return-21.15%-73.83%
1-year return-13.14%-88.79%
5-year return-96.13%—
Forward P/E13.23—
EPS (TTM)$-1.16$-16.87
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.07$55.90
52-week low$1.80$2.58
Distance from 52-week high-33.22%-90.07%
Average volume34.40K1.36M
Shares outstanding10.87M4.76M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AYTU has outperformed SHPH by 75.7 percentage points over the past year.

AYTU vs SHPH FAQ

Which is bigger, Aytu BioPharma or Shuttle Pharmaceuticals?

Shuttle Pharmaceuticals (SHPH) is larger, with a market capitalization of $26.44M compared with $22.28M for Aytu BioPharma (AYTU).

Which stock has performed better over the past year, AYTU or SHPH?

AYTU returned -13.14% over the past 12 months, compared with -88.79% for SHPH (price return, excluding dividends). Past performance does not predict future results.

Are Aytu BioPharma and Shuttle Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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