MetaCap

Biohaven (BHVN) vs Septerna (SEPN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Septerna (SEPN) has outperformed Biohaven (BHVN) over the past year, gaining 65.8% versus a loss of 29.9%. Biohaven is the larger company by market cap ($1.82 billion vs $1.79 billion), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

BHVN-29.89%SEPN+65.82%
+116%+27%-63%
Oct 9, 20251 yearOct 9, 2026
BHVN-77.14%SEPN+79.30%
+118%+12%-94%
Oct 21, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

BHVN versus SEPN key metrics
MetricBHVNSEPN
Share price$12.08$38.37
Market cap$1.82B$1.79B
1-day change+1.26%+3.98%
YTD return+7.00%+37.63%
1-year return-29.89%+65.82%
EPS (TTM)$-4.62$-0.56
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$45.95M
Revenue growth (YoY)—+4174.51%
Net income (latest FY)$-738.82M$-48.88M
Operating margin—-148.63%
Net margin—-106.37%
52-week high$18.57$51.10
52-week low$7.48$17.55
Distance from 52-week high-34.93%-24.91%
Analyst consensusbuystrong_buy
Avg. price target upside+76.08%+41.31%
Average volume2.63M390.66K
Shares outstanding151.04M46.68M
Employees274123
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • SEPN has outperformed BHVN by 95.7 percentage points over the past year.

About Biohaven

BHVN stock →

Biohaven Ltd., a biopharmaceutical company, focuses on the discovery, development, and commercialization of treatments for immunology, neuroscience, and oncology therapeutic areas worldwide. It develops BHV-1300, which is in Phase 2 clinical trial to treat Graves' disease and rheumatoid arthritis; BHV-1400 that is in Phase 2 clinical trial for treating IgA nephropathy; BHV-1600, which is in Phase 1 clinical trial for the treatment of peripartum cardiomyopathy; BHV-8000 that is in Phase 3 clinical trial for treating Parkinson's disease; Opakalim, which is in Phase 3 clinical trial for the treatment of focal epilepsy; BHV-2100 that is in Phase 2 clinical trial for the treatment of pain disorders; and BHV-2000, which is in Phase 2 clinical trial for treating obesity.

Health Care · Biotechnology: Pharmaceutical Preparations · 274 employees

About Septerna

SEPN stock →

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 123 employees

BHVN vs SEPN FAQ

Which is bigger, Biohaven or Septerna?

Biohaven (BHVN) is larger, with a market capitalization of $1.82B compared with $1.79B for Septerna (SEPN).

Which stock has performed better over the past year, BHVN or SEPN?

SEPN returned +65.82% over the past 12 months, compared with -29.89% for BHVN (price return, excluding dividends). Past performance does not predict future results.

Are Biohaven and Septerna in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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