CareDx (CDNA) vs Personalis (PSNL)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
CareDx (CDNA) has outperformed Personalis (PSNL) over the past year, gaining 329.7% versus a gain of 111.4%. Over five years, CDNA leads with a -11.2% price change compared with -19.8% for PSNL. CareDx is the larger company by market cap ($3.26 billion vs $1.71 billion), about 1.9 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | CDNA | PSNL |
|---|---|---|
| Share price | $63.04 | $16.00 |
| Market cap | $3.26B | $1.71B |
| 1-day change | -1.18% | -0.19% |
| YTD return | +234.61% | +101.01% |
| 1-year return | +329.72% | +111.36% |
| 5-year return | -11.21% | -19.76% |
| P/E ratio (TTM) | 30.31 | — |
| Forward P/E | 48.87 | — |
| EPS (TTM) | $2.08 | $-1.09 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $379.81M | — |
| Revenue growth (YoY) | +13.79% | — |
| Net income (latest FY) | $-21.35M | — |
| Operating margin | -8.10% | — |
| Net margin | -5.62% | — |
| 52-week high | $72.51 | $18.89 |
| 52-week low | $13.95 | $4.96 |
| Distance from 52-week high | -13.06% | -15.30% |
| Analyst consensus | buy | hold |
| Avg. price target upside | -6.68% | -5.19% |
| Average volume | 1.28M | 3.59M |
| Shares outstanding | 51.73M | 106.80M |
| Employees | 761 | 259 |
| Sector | Health Care | Health Care |
| Industry | Medical Specialities | Medical Specialities |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- CDNA has outperformed PSNL by 218.4 percentage points over the past year.
About CareDx
CDNA stock →CareDx, Inc. provides solutions for improving outcomes for transplant patients and advancing organ health in the United States and internationally.
Health Care · Medical Specialities · 761 employees
About Personalis
PSNL stock →Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally.
Health Care · Medical Specialities · 259 employees
CDNA vs PSNL FAQ
Which is bigger, CareDx or Personalis?
CareDx (CDNA) is larger, with a market capitalization of $3.26B compared with $1.71B for Personalis (PSNL).
Which stock has performed better over the past year, CDNA or PSNL?
CDNA returned +329.72% over the past 12 months, compared with +111.36% for PSNL (price return, excluding dividends). Past performance does not predict future results.
Are CareDx and Personalis in the same industry?
Yes. Both are classified in the Medical Specialities industry within the Health Care sector.