MetaCap

CG Oncology (CGON) vs Relay Therapeutics (RLAY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Relay Therapeutics (RLAY) has outperformed CG Oncology (CGON) over the past year, gaining 207.9% versus a gain of 64.2%. CG Oncology is the larger company by market cap ($5.53 billion vs $3.93 billion), about 1.4 times the size. Relay Therapeutics converts more of its revenue into profit, with a net margin of -1800.6% versus -3985.0%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CGON+64.16%RLAY+207.89%
+269%+127%-15%
Oct 7, 20251 yearOct 7, 2026
CGON+78.08%RLAY+84.67%
+138%+24%-90%
Jan 22, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CGON versus RLAY key metrics
MetricCGONRLAY
Share price$62.38$17.95
Market cap$5.53B$3.93B
1-day change-1.98%-4.22%
YTD return+50.24%+112.17%
1-year return+64.16%+207.89%
5-year return—-47.38%
EPS (TTM)$-2.69$-1.49
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$4.04M$15.36M
Revenue growth (YoY)+254.70%+53.44%
Net income (latest FY)$-161.00M$-276.48M
Operating margin-4722.13%-1971.59%
Net margin-3985.02%-1800.58%
52-week high$80.97$21.27
52-week low$35.80$5.83
Distance from 52-week high-22.96%-15.61%
Analyst consensusnonestrong_buy
Avg. price target upside+46.01%+53.65%
Average volume891.79K2.81M
Shares outstanding88.64M219.14M
Employees142202
SectorHealthcareHealth Care
IndustryBiotechnologyBiotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RLAY has outperformed CGON by 143.7 percentage points over the past year.
  • Relay Therapeutics is more profitable, keeping -1800.6 cents of every revenue dollar as net income versus -3985.0 cents for CG Oncology.
  • CG Oncology grew revenue faster in its latest fiscal year (+254.70% vs +53.44%).
  • The two companies sit in different sectors: CG Oncology in Healthcare and Relay Therapeutics in Health Care.

About CG Oncology

CGON stock →

CG Oncology, Inc., a late-stage clinical biopharmaceutical company, develops and commercializes cretostimogene grenadenorepvec for patients with bladder cancer in the United States. The company's product candidate is cretostimogene, an investigational oncolytic immunotherapy, which is in phase 2 clinical trials of cretostimogene in patients with high-risk NMIBC after BCG failure; a phase 3 clinical trials to evaluate the safety and efficacy of cretostimogene as monotherapy in the treatment of patients who have received adequate BCG therapy with high-risk BCG-unresponsive, CIS-containing NMIBC and BCG-unresponsive Ta, or T1 papillary tumors; phase 3 BOND-003 Cohort C trials as a single agent; phase 3 BOND-003 Cohort P as a single agent in patients with BCG-UR papillary-only NMIBC.

Healthcare · Biotechnology · 142 employees

About Relay Therapeutics

RLAY stock →

Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 202 employees

CGON vs RLAY FAQ

Which is bigger, CG Oncology or Relay Therapeutics?

CG Oncology (CGON) is larger, with a market capitalization of $5.53B compared with $3.93B for Relay Therapeutics (RLAY).

Which stock has performed better over the past year, CGON or RLAY?

RLAY returned +207.89% over the past 12 months, compared with +64.16% for CGON (price return, excluding dividends). Past performance does not predict future results.

Are CG Oncology and Relay Therapeutics in the same industry?

No. CG Oncology is in the Healthcare sector, while Relay Therapeutics is in Health Care.

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