MetaCap

Coya Therapeutics (COYA) vs Polaryx Therapeutics (PLYX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

Coya Therapeutics is the larger company by market cap ($99.7 million vs $93.7 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

COYA-10.34%PLYX-94.63%
+34%-33%-101%
Feb 2, 20261 yearOct 16, 2026
COYA-12.19%PLYX-78.90%
+26%-29%-84%
Feb 2, 20265 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

COYA versus PLYX key metrics
MetricCOYAPLYX
Share price$4.25$1.88
Market cap$99.70M$93.71M
1-day change-2.07%-3.59%
YTD return-26.72%—
1-year return-33.18%—
EPS (TTM)$-1.07$-0.14
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$7.95M—
Revenue growth (YoY)+123.57%—
Net income (latest FY)$-21.23M$-8.98M
Operating margin-283.87%—
Net margin-267.14%—
52-week high$7.55$48.91
52-week low$3.71$1.85
Distance from 52-week high-43.71%-96.16%
Analyst consensusstrong_buynone
Avg. price target upside+257.88%+298.94%
Average volume140.71K70.79K
Shares outstanding23.46M49.85M
Employees82
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Coya Therapeutics

COYA stock →

Coya Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of proprietary therapies to enhance the function of regulatory T cells (Tregs). Its candidate product pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy.

Health Care · Biotechnology: Pharmaceutical Preparations · 8 employees

About Polaryx Therapeutics

PLYX stock →

Polaryx Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of disease-modifying therapies for rare and pediatric lysosomal storage disorders in the United States. Its pipeline includes PLX-100, a preclinical stage orally administrable combination therapy; PLX-200, a repurposed oral small molecule for the treatment of LSDs; PLX-300, a preclinical stage orally administrable combination therapy; and PLX-400, a preclinical stage novel gene therapy candidate.

Health Care · Biotechnology: Pharmaceutical Preparations · 2 employees

COYA vs PLYX FAQ

Which is bigger, Coya Therapeutics or Polaryx Therapeutics?

Coya Therapeutics (COYA) is larger, with a market capitalization of $99.70M compared with $93.71M for Polaryx Therapeutics (PLYX).

Are Coya Therapeutics and Polaryx Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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