MetaCap

Caribou Biosciences (CRBU) vs Kalaris Therapeutics (KLRS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Kalaris Therapeutics (KLRS) has outperformed Caribou Biosciences (CRBU) over the past year, losing 62.1% versus a loss of 82.0%. Over five years, CRBU leads with a -97.7% price change compared with -99.5% for KLRS. Kalaris Therapeutics is the larger company by market cap ($59.5 million vs $51.6 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CRBU-82.04%KLRS-62.06%
+74%-8%-89%
Oct 8, 20251 yearOct 8, 2026
CRBU-97.49%KLRS-99.51%
+23%-41%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CRBU versus KLRS key metrics
MetricCRBUKLRS
Share price$0.4812$2.50
Market cap$51.59M$59.51M
1-day change-22.06%-2.34%
YTD return-69.74%-70.38%
1-year return-82.04%-62.06%
5-year return-97.69%-99.51%
EPS (TTM)$-1.08$-2.02
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.54$11.88
52-week low$0.45$2.35
Distance from 52-week high-86.39%-78.96%
Analyst consensusbuystrong_buy
Avg. price target upside+1094.93%+648.40%
Average volume2.14M252.88K
Shares outstanding107.21M23.80M
Employees9720
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • KLRS has outperformed CRBU by 20.0 percentage points over the past year.

About Caribou Biosciences

CRBU stock →

Caribou Biosciences, Inc. operates as a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 97 employees

About Kalaris Therapeutics

KLRS stock →

Kalaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of treatments for prevalent retinal diseases. It develops TH103, a clinical-stage anti-vascular endothelial growth factor (VEGF) drug for the treatment of neovascular age-related macular degeneration (nAMD), which is in Phase 1b/2, as well as for the treatment of other exudative and neovascular retinal diseases.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 20 employees

CRBU vs KLRS FAQ

Which is bigger, Caribou Biosciences or Kalaris Therapeutics?

Kalaris Therapeutics (KLRS) is larger, with a market capitalization of $59.51M compared with $51.59M for Caribou Biosciences (CRBU).

Which stock has performed better over the past year, CRBU or KLRS?

KLRS returned -62.06% over the past 12 months, compared with -82.04% for CRBU (price return, excluding dividends). Past performance does not predict future results.

Are Caribou Biosciences and Kalaris Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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