MetaCap

Caribou Biosciences (CRBU) vs Pelthos Therapeutics (PTHS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Pelthos Therapeutics (PTHS) has outperformed Caribou Biosciences (CRBU) over the past year, losing 24.5% versus a loss of 82.0%. Pelthos Therapeutics is the larger company by market cap ($78.5 million vs $51.6 million), about 1.5 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CRBU-82.04%PTHS-24.47%
+44%-22%-88%
Oct 8, 20251 yearOct 8, 2026
CRBU-93.04%PTHS-57.29%
+18%-40%-98%
Feb 12, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CRBU versus PTHS key metrics
MetricCRBUPTHS
Share price$0.4812$20.50
Market cap$51.59M$78.48M
1-day change-22.06%-2.33%
YTD return-69.74%-33.87%
1-year return-82.04%-24.47%
5-year return-97.69%—
EPS (TTM)$-1.08$-27.53
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.54$37.50
52-week low$0.45$18.19
Distance from 52-week high-86.39%-45.33%
Analyst consensusbuystrong_buy
Avg. price target upside+1094.93%+159.22%
Average volume2.14M60.07K
Shares outstanding107.21M3.83M
Employees9792
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PTHS has outperformed CRBU by 57.6 percentage points over the past year.

About Caribou Biosciences

CRBU stock →

Caribou Biosciences, Inc. operates as a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 97 employees

About Pelthos Therapeutics

PTHS stock →

Pelthos Therapeutics Inc., a bio-pharmaceutical company, develops and commercializes therapeutic products to help patients with unmet treatment burdens. The company offers ZELSUVMI for the treatment of molluscum contagiosum in adults and children 1 year of age and older; XEPI, (ozenoxacin) cream, a quinolone antimicrobial for the treatment of impetigo due to Staphylococcus aureus or Streptococcus pyogenes in adult and pediatric patients 2 months of age and older; and XEGLYZE, a pediculicide indicated for topical treatment of head lice infestation in patients 6 months of age and older.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 92 employees

CRBU vs PTHS FAQ

Which is bigger, Caribou Biosciences or Pelthos Therapeutics?

Pelthos Therapeutics (PTHS) is larger, with a market capitalization of $78.48M compared with $51.59M for Caribou Biosciences (CRBU).

Which stock has performed better over the past year, CRBU or PTHS?

PTHS returned -24.47% over the past 12 months, compared with -82.04% for CRBU (price return, excluding dividends). Past performance does not predict future results.

Are Caribou Biosciences and Pelthos Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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