Danaher (DHR) vs OPKO Health (OPK)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Danaher (DHR) has outperformed OPKO Health (OPK) over the past year, gaining 4.7% versus a loss of 11.6%. Over five years, DHR leads with a -18.2% price change compared with -63.2% for OPK. Danaher is the larger company by market cap ($152.87 billion vs $1.02 billion), about 149.5 times the size.
Danaher pays a dividend yielding 0.66%, while OPKO Health does not currently pay one.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | DHR | OPK |
|---|---|---|
| Share price | $217.46 | $1.37 |
| Market cap | $152.87B | $1.02B |
| 1-day change | -0.47% | -1.44% |
| YTD return | -4.56% | +8.73% |
| 1-year return | +4.66% | -11.61% |
| 5-year return | -18.22% | -63.17% |
| P/E ratio (TTM) | 38.76 | — |
| Forward P/E | 23.39 | — |
| EPS (TTM) | $5.61 | $-0.09 |
| Dividend yield | 0.66% | 0.00% |
| Annual dividend | $1.44 | $0.00 |
| Revenue (latest FY) | $24.57B | — |
| Revenue growth (YoY) | +2.90% | — |
| Net income (latest FY) | $3.61B | — |
| Gross margin | 59.11% | — |
| Operating margin | 19.09% | — |
| Net margin | 14.71% | — |
| 52-week high | $242.80 | $1.75 |
| 52-week low | $160.93 | $0.98 |
| Distance from 52-week high | -10.44% | -21.71% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +9.93% | +219.71% |
| Average volume | 4.70M | 3.35M |
| Shares outstanding | 702.99M | 746.33M |
| Employees | 58,000 | 2,275 |
| Sector | Industrials | Health Care |
| Industry | Industrial Machinery/Components | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Danaher is about 149.5 times larger than OPKO Health by market value ($152.87B vs $1.02B).
- DHR has outperformed OPK by 16.3 percentage points over the past year.
- The two companies sit in different sectors: Danaher in Industrials and OPKO Health in Health Care.
About Danaher
DHR stock →Danaher Corporation designs, manufactures, and markets professional, medical, research, and industrial products and services in the United States, China, and internationally. The company operates through Biotechnology, Life Sciences, and Diagnostics segments.
Industrials · Industrial Machinery/Components · 58,000 employees
About OPKO Health
OPK stock →OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally.
Health Care · Biotechnology: Pharmaceutical Preparations · 2,275 employees
DHR vs OPK FAQ
Which is bigger, Danaher or OPKO Health?
Danaher (DHR) is larger, with a market capitalization of $152.87B compared with $1.02B for OPKO Health (OPK).
Which stock has performed better over the past year, DHR or OPK?
DHR returned +4.66% over the past 12 months, compared with -11.61% for OPK (price return, excluding dividends). Past performance does not predict future results.
Which pays a higher dividend, Danaher or OPKO Health?
Danaher pays a dividend yielding 0.66%, while OPKO Health does not currently pay a regular dividend.
Are Danaher and OPKO Health in the same industry?
No. Danaher is in the Industrials sector, while OPKO Health is in Health Care.