MetaCap

DarioHealth (DRIO) vs OptimizeRx (OPRX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

OptimizeRx (OPRX) has outperformed DarioHealth (DRIO) over the past year, losing 54.1% versus a loss of 66.8%. Over five years, OPRX leads with a -90.1% price change compared with -98.3% for DRIO. OptimizeRx is the larger company by market cap ($156.0 million vs $56.8 million), about 2.7 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

DRIO-66.83%OPRX-54.06%
+24%-28%-80%
Oct 8, 20251 yearOct 8, 2026
DRIO-97.87%OPRX-89.50%
+54%-26%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

DRIO versus OPRX key metrics
MetricDRIOOPRX
Share price$5.80$8.28
Market cap$56.84M$155.96M
1-day change+4.69%-1.19%
YTD return-52.28%-31.65%
1-year return-66.83%-54.06%
5-year return-98.32%-90.10%
P/E ratio (TTM)—34.50
Forward P/E—7.93
EPS (TTM)$-2.28$0.24
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$16.50$22.25
52-week low$5.37$4.54
Distance from 52-week high-64.85%-62.79%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+134.48%+52.17%
Average volume25.00K203.38K
Shares outstanding9.80M18.84M
Employees160132
SectorHealth CareConsumer Discretionary
IndustryMedical/Dental InstrumentsBusiness Services

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • OptimizeRx is about 2.7 times larger than DarioHealth by market value ($155.96M vs $56.84M).
  • OPRX has outperformed DRIO by 12.8 percentage points over the past year.
  • The two companies sit in different sectors: DarioHealth in Health Care and OptimizeRx in Consumer Discretionary.

About DarioHealth

DRIO stock →

DarioHealth Corp. operates as a digital health company in the United States and internationally.

Health Care · Medical/Dental Instruments · 160 employees

About OptimizeRx

OPRX stock →

OptimizeRx Corporation operates as a digital healthcare technology company. It offers Dynamic Audience Activation Platform, which generates dynamic audiences with predictive analytics through machine learning methods; Micro-Neighborhood Targeting, which creates consumer audiences using a privacy-first process; Profiler, which provides insights into its customers' target consumers; banner messages, including brand messaging, therapeutic support messaging, affordability messaging, limited distribution drug information, and patient support program messaging through healthcare professionals; and media execution solutions, which deliver messages through consumer omnichannel network, including through programmatic display, programmatic connected television/over-the-top, programmatic social media, addressable television, digital out-of-home, programmatic audio, and email/direct mail.

Consumer Discretionary · Business Services · 132 employees

DRIO vs OPRX FAQ

Which is bigger, DarioHealth or OptimizeRx?

OptimizeRx (OPRX) is larger, with a market capitalization of $155.96M compared with $56.84M for DarioHealth (DRIO).

Which stock has performed better over the past year, DRIO or OPRX?

OPRX returned -54.06% over the past 12 months, compared with -66.83% for DRIO (price return, excluding dividends). Past performance does not predict future results.

Are DarioHealth and OptimizeRx in the same industry?

No. DarioHealth is in the Health Care sector, while OptimizeRx is in Consumer Discretionary.

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