MetaCap

Dyne Therapeutics (DYN) vs Precigen (PGEN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Precigen (PGEN) has outperformed Dyne Therapeutics (DYN) over the past year, gaining 127.8% versus a gain of 14.5%. Over five years, PGEN leads with a +62.2% price change compared with +7.3% for DYN. Dyne Therapeutics is the larger company by market cap ($2.98 billion vs $2.70 billion), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

DYN+14.48%PGEN+127.79%
+167%+76%-15%
Oct 7, 20251 yearOct 7, 2026
DYN+11.68%PGEN+61.46%
+241%+70%-101%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

DYN versus PGEN key metrics
MetricDYNPGEN
Share price$15.97$7.54
Market cap$2.98B$2.70B
1-day change+3.70%-0.13%
YTD return-18.35%+80.38%
1-year return+14.48%+127.79%
5-year return+7.33%+62.15%
EPS (TTM)$-3.30$-1.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$9.68M
Revenue growth (YoY)—+146.73%
Net income (latest FY)$-446.21M$-250.64M
Operating margin—-1141.13%
Net margin—-2588.21%
52-week high$27.31$8.98
52-week low$13.73$2.99
Distance from 52-week high-41.51%-16.04%
Analyst consensusstrong_buybuy
Avg. price target upside+125.42%+81.03%
Average volume2.77M5.03M
Shares outstanding186.75M358.04M
Employees289160
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PGEN has outperformed DYN by 113.3 percentage points over the past year.

About Dyne Therapeutics

DYN stock →

Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. The company is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics.

Health Care · Biotechnology: Pharmaceutical Preparations · 289 employees

About Precigen

PGEN stock →

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients.

Health Care · Biotechnology: Pharmaceutical Preparations · 160 employees

DYN vs PGEN FAQ

Which is bigger, Dyne Therapeutics or Precigen?

Dyne Therapeutics (DYN) is larger, with a market capitalization of $2.98B compared with $2.70B for Precigen (PGEN).

Which stock has performed better over the past year, DYN or PGEN?

PGEN returned +127.79% over the past 12 months, compared with +14.48% for DYN (price return, excluding dividends). Past performance does not predict future results.

Are Dyne Therapeutics and Precigen in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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