MetaCap

Erasca (ERAS) vs Ligand Pharmaceuticals (LGND)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Erasca (ERAS) has outperformed Ligand Pharmaceuticals (LGND) over the past year, gaining 536.2% versus a gain of 59.9%. Over five years, LGND leads with a +263.0% price change compared with -13.1% for ERAS. Ligand Pharmaceuticals is the larger company by market cap ($6.07 billion vs $5.57 billion), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ERAS+536.21%LGND+59.90%
+866%+408%-51%
Oct 8, 20251 yearOct 8, 2026
ERAS-11.00%LGND+270.14%
+321%+104%-113%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ERAS versus LGND key metrics
MetricERASLGND
Share price$15.92$304.35
Market cap$5.57B$6.07B
1-day change+2.94%+3.17%
YTD return+315.59%+56.03%
1-year return+536.21%+59.90%
5-year return-13.15%+263.03%
P/E ratio (TTM)—32.07
Forward P/E—25.47
EPS (TTM)$-0.95$9.49
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$268.09M
Revenue growth (YoY)—+60.40%
Net income (latest FY)$-124.55M$124.45M
Operating margin—15.29%
Net margin—46.42%
52-week high$24.28$326.63
52-week low$2.11$175.89
Distance from 52-week high-34.45%-6.82%
Analyst consensusnonestrong_buy
Avg. price target upside+51.49%+13.11%
Average volume4.37M258.59K
Shares outstanding349.76M19.94M
Employees10347
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ERAS has outperformed LGND by 476.3 percentage points over the past year.

About Erasca

ERAS stock →

Erasca, Inc., a clinical-stage precision oncology company, focuses on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers. The company's product pipeline includes ERAS-0015, a pan-RAS molecular glue for the treatment of patients with RAS-mutated solid tumors; ERAS-4001, a pan-KRAS inhibitor for the treatment of patients with KRAS-mutated solid tumors; and ERAS-12, an investigational EGFR D2/D3 biparatopic antibody (bpAb) for the treatment of EGFR and RAS/MAPK solid tumors.

Health Care · Biotechnology: Pharmaceutical Preparations · 103 employees

About Ligand Pharmaceuticals

LGND stock →

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma.

Health Care · Biotechnology: Pharmaceutical Preparations · 47 employees

ERAS vs LGND FAQ

Which is bigger, Erasca or Ligand Pharmaceuticals?

Ligand Pharmaceuticals (LGND) is larger, with a market capitalization of $6.07B compared with $5.57B for Erasca (ERAS).

Which stock has performed better over the past year, ERAS or LGND?

ERAS returned +536.21% over the past 12 months, compared with +59.90% for LGND (price return, excluding dividends). Past performance does not predict future results.

Are Erasca and Ligand Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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