Ligand Pharmaceuticals (LGND) vs Mirum Pharmaceuticals (MIRM)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Ligand Pharmaceuticals (LGND) has outperformed Mirum Pharmaceuticals (MIRM) over the past year, gaining 59.9% versus a gain of 11.7%. Over five years, MIRM leads with a +375.2% price change compared with +263.0% for LGND. Ligand Pharmaceuticals is the larger company by market cap ($6.02 billion vs $5.58 billion), about 1.1 times the size.
Ligand Pharmaceuticals converts more of its revenue into profit, with a net margin of 46.4% versus -4.5%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | LGND | MIRM |
|---|---|---|
| Share price | $301.81 | $86.01 |
| Market cap | $6.02B | $5.58B |
| 1-day change | +2.31% | +5.73% |
| YTD return | +56.03% | +2.99% |
| 1-year return | +59.90% | +11.67% |
| 5-year return | +263.03% | +375.18% |
| P/E ratio (TTM) | 31.80 | — |
| Forward P/E | 25.26 | — |
| EPS (TTM) | $9.49 | $-14.10 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $268.09M | $521.31M |
| Revenue growth (YoY) | +60.40% | +54.74% |
| Net income (latest FY) | $124.45M | $-23.36M |
| Operating margin | 15.29% | -4.25% |
| Net margin | 46.42% | -4.48% |
| 52-week high | $326.63 | $130.00 |
| 52-week low | $175.89 | $63.23 |
| Distance from 52-week high | -7.60% | -33.84% |
| Analyst consensus | strong_buy | strong_buy |
| Avg. price target upside | +14.06% | +69.50% |
| Average volume | 258.59K | 695.76K |
| Shares outstanding | 19.94M | 64.93M |
| Employees | 47 | 433 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- LGND has outperformed MIRM by 48.2 percentage points over the past year.
- Ligand Pharmaceuticals is more profitable, keeping 46.4 cents of every revenue dollar as net income versus -4.5 cents for Mirum Pharmaceuticals.
- Ligand Pharmaceuticals grew revenue faster in its latest fiscal year (+60.40% vs +54.74%).
About Ligand Pharmaceuticals
LGND stock →Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma.
Health Care · Biotechnology: Pharmaceutical Preparations · 47 employees
About Mirum Pharmaceuticals
MIRM stock →Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally.
Health Care · Biotechnology: Pharmaceutical Preparations · 433 employees
LGND vs MIRM FAQ
Which is bigger, Ligand Pharmaceuticals or Mirum Pharmaceuticals?
Ligand Pharmaceuticals (LGND) is larger, with a market capitalization of $6.02B compared with $5.58B for Mirum Pharmaceuticals (MIRM).
Which stock has performed better over the past year, LGND or MIRM?
LGND returned +59.90% over the past 12 months, compared with +11.67% for MIRM (price return, excluding dividends). Past performance does not predict future results.
Are Ligand Pharmaceuticals and Mirum Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.