Edwards Lifesciences (EW) vs Intuitive Surgical (ISRG)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Edwards Lifesciences (EW) has outperformed Intuitive Surgical (ISRG) over the past year, gaining 11.8% versus a loss of 6.0%. Over five years, ISRG leads with a +25.0% price change compared with -23.5% for EW. Intuitive Surgical is the larger company by market cap ($146.44 billion vs $49.44 billion), about 3.0 times the size.
On valuation, Edwards Lifesciences trades at a lower forward P/E (25.4x vs 34.2x for Intuitive Surgical). Intuitive Surgical converts more of its revenue into profit, with a net margin of 28.4% versus 17.7%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | EW | ISRG |
|---|---|---|
| Share price | $85.78 | $414.52 |
| Market cap | $49.44B | $146.44B |
| 1-day change | -0.81% | +2.41% |
| YTD return | +0.62% | -26.81% |
| 1-year return | +11.81% | -5.99% |
| 5-year return | -23.52% | +25.04% |
| P/E ratio (TTM) | 51.06 | 46.42 |
| Forward P/E | 25.40 | 34.22 |
| EPS (TTM) | $1.68 | $8.93 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $6.07B | $10.06B |
| Revenue growth (YoY) | +11.55% | +20.51% |
| Net income (latest FY) | $1.07B | $2.86B |
| Gross margin | 78.01% | 66.00% |
| Operating margin | 20.84% | 29.27% |
| Net margin | 17.69% | 28.38% |
| 52-week high | $96.29 | $603.88 |
| 52-week low | $72.30 | $328.57 |
| Distance from 52-week high | -10.91% | -31.36% |
| Analyst consensus | buy | buy |
| Avg. price target upside | +18.86% | +15.19% |
| Average volume | 3.82M | 2.93M |
| Shares outstanding | 576.40M | 353.28M |
| Employees | 16,000 | 17,021 |
| Sector | Healthcare | Health Care |
| Industry | Medical Devices | Industrial Specialties |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Intuitive Surgical is about 3.0 times larger than Edwards Lifesciences by market value ($146.44B vs $49.44B).
- EW has outperformed ISRG by 17.8 percentage points over the past year.
- Intuitive Surgical is more profitable, keeping 28.4 cents of every revenue dollar as net income versus 17.7 cents for Edwards Lifesciences.
- Intuitive Surgical grew revenue faster in its latest fiscal year (+20.51% vs +11.55%).
- The two companies sit in different sectors: Edwards Lifesciences in Healthcare and Intuitive Surgical in Health Care.
About Edwards Lifesciences
EW stock →Edwards Lifesciences Corporation provides products and technologies to treat advanced cardiovascular diseases in the United States, Europe, Japan, and internationally. It offers transcatheter heart valve replacement products for minimally invasive replacement of aortic heart valves under the Edwards SAPIEN family of valves system; and transcatheter heart valve repair and replacement products to treat mitral and tricuspid valve diseases under the PASCAL and EVOQUE brands.
Healthcare · Medical Devices · 16,000 employees
About Intuitive Surgical
ISRG stock →Intuitive Surgical, Inc. develops, manufactures, and markets products that enable physicians and healthcare providers to enhance the quality of and access to minimally invasive care in the United States and internationally.
Health Care · Industrial Specialties · 17,021 employees
EW vs ISRG FAQ
Which is bigger, Edwards Lifesciences or Intuitive Surgical?
Intuitive Surgical (ISRG) is larger, with a market capitalization of $146.44B compared with $49.44B for Edwards Lifesciences (EW).
Which stock has performed better over the past year, EW or ISRG?
EW returned +11.81% over the past 12 months, compared with -5.99% for ISRG (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, EW or ISRG?
ISRG has the lower trailing P/E at 46.4, versus 51.1 for EW. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Edwards Lifesciences and Intuitive Surgical in the same industry?
No. Edwards Lifesciences is in the Healthcare sector, while Intuitive Surgical is in Health Care.