MetaCap

Edgewise Therapeutics (EWTX) vs Mirum Pharmaceuticals (MIRM)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Edgewise Therapeutics (EWTX) has outperformed Mirum Pharmaceuticals (MIRM) over the past year, gaining 161.4% versus a gain of 9.4%. Over five years, MIRM leads with a +371.0% price change compared with +123.1% for EWTX. Mirum Pharmaceuticals is the larger company by market cap ($5.26 billion vs $4.20 billion), about 1.3 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

EWTX+161.36%MIRM+9.36%
+231%+103%-25%
Oct 7, 20251 yearOct 7, 2026
EWTX+116.23%MIRM+383.45%
+689%+292%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

EWTX versus MIRM key metrics
MetricEWTXMIRM
Share price$38.65$81.01
Market cap$4.20B$5.26B
1-day change-2.34%+0.46%
YTD return+59.46%+2.09%
1-year return+161.36%+9.36%
5-year return+123.06%+371.03%
EPS (TTM)$-1.86$-14.10
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$521.31M
Revenue growth (YoY)—+54.74%
Net income (latest FY)$-167.79M$-23.36M
Operating margin—-4.25%
Net margin—-4.48%
52-week high$48.51$130.00
52-week low$14.25$63.23
Distance from 52-week high-20.34%-37.68%
Analyst consensusbuystrong_buy
Avg. price target upside+36.16%+79.97%
Average volume1.35M698.74K
Shares outstanding108.60M64.93M
Employees127433
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • EWTX has outperformed MIRM by 152.0 percentage points over the past year.

About Edgewise Therapeutics

EWTX stock →

Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders. Its lead product candidate, sevasemten, an orally administered small molecule that is in Phase II clinical trials, designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy.

Health Care · Biotechnology: Pharmaceutical Preparations · 127 employees

About Mirum Pharmaceuticals

MIRM stock →

Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 433 employees

EWTX vs MIRM FAQ

Which is bigger, Edgewise Therapeutics or Mirum Pharmaceuticals?

Mirum Pharmaceuticals (MIRM) is larger, with a market capitalization of $5.26B compared with $4.20B for Edgewise Therapeutics (EWTX).

Which stock has performed better over the past year, EWTX or MIRM?

EWTX returned +161.36% over the past 12 months, compared with +9.36% for MIRM (price return, excluding dividends). Past performance does not predict future results.

Are Edgewise Therapeutics and Mirum Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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