MetaCap

Greenwich LifeSciences (GLSI) vs Pyxis Oncology (PYXS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Greenwich LifeSciences (GLSI) has outperformed Pyxis Oncology (PYXS) over the past year, gaining 32.3% versus a loss of 31.6%. Over five years, GLSI leads with a -60.1% price change compared with -83.1% for PYXS. Pyxis Oncology is the larger company by market cap ($241.9 million vs $234.9 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

GLSI+32.28%PYXS-31.62%
+206%+65%-76%
Oct 8, 20251 yearOct 8, 2026
GLSI-59.40%PYXS-84.92%
+7%-46%-98%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

GLSI versus PYXS key metrics
MetricGLSIPYXS
Share price$16.00$2.03
Market cap$234.85M$241.90M
1-day change+5.68%+1.76%
YTD return-27.94%+73.04%
1-year return+32.28%-31.62%
5-year return-60.12%-83.09%
EPS (TTM)$-1.53$-1.40
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$34.10$5.55
52-week low$7.78$1.03
Distance from 52-week high-53.08%-63.51%
Analyst consensusnonenone
Avg. price target upside+256.25%+328.15%
Average volume138.91K1.26M
Shares outstanding14.68M119.46M
Employees—56
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • GLSI has outperformed PYXS by 63.9 percentage points over the past year.

About Greenwich LifeSciences

GLSI stock →

Greenwich LifeSciences, Inc., a clinical-stage biopharmaceutical company, develops novel cancer immunotherapies for breast cancer and other HER2/neu-expressing cancers in the United States. Its lead product candidate is GP2, a HER2/neu transmembrane peptide, which is in Phase III clinical trial to prevent breast cancer recurrences in patients.

Health Care · Biotechnology: Pharmaceutical Preparations

About Pyxis Oncology

PYXS stock →

Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat solid tumors. Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; PYX-102, an investigational immunotherapeutic targeting KLRG1, an inhibitory receptor on T cells and NK cells, with potential for use as monotherapy or in combination treatments; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors.

Health Care · Biotechnology: Pharmaceutical Preparations · 56 employees

GLSI vs PYXS FAQ

Which is bigger, Greenwich LifeSciences or Pyxis Oncology?

Pyxis Oncology (PYXS) is larger, with a market capitalization of $241.90M compared with $234.85M for Greenwich LifeSciences (GLSI).

Which stock has performed better over the past year, GLSI or PYXS?

GLSI returned +32.28% over the past 12 months, compared with -31.62% for PYXS (price return, excluding dividends). Past performance does not predict future results.

Are Greenwich LifeSciences and Pyxis Oncology in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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