MetaCap

Werewolf Therapeutics (HOWL) vs Instil Bio (TIL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Werewolf Therapeutics (HOWL) has outperformed Instil Bio (TIL) over the past year, losing 51.6% versus a loss of 68.0%. Over five years, HOWL leads with a -94.7% price change compared with -98.2% for TIL. Instil Bio is the larger company by market cap ($44.5 million vs $44.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

HOWL-51.60%TIL-68.05%
+7%-40%-88%
Oct 8, 20251 yearOct 8, 2026
HOWL-94.28%TIL-98.17%
+30%-37%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

HOWL versus TIL key metrics
MetricHOWLTIL
Share price$0.91$6.56
Market cap$44.23M$44.49M
1-day change-1.10%-4.23%
YTD return+43.53%-40.36%
1-year return-51.60%-68.05%
5-year return-94.67%-98.17%
EPS (TTM)$-0.73$-4.43
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$1.94$21.98
52-week low$0.27$5.67
Distance from 52-week high-53.02%-70.15%
Analyst consensusnonenone
Avg. price target upside+669.23%+6.71%
Average volume6.80M12.54K
Shares outstanding48.60M6.78M
Employees3917
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • HOWL has outperformed TIL by 16.5 percentage points over the past year.

About Werewolf Therapeutics

HOWL stock →

Werewolf Therapeutics, Inc., a biopharmaceutical company, engages in the development of therapeutics engineered to stimulate the body's immune system for the treatment of cancer and other immune-mediated conditions. The company designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies through its proprietary PREDATOR platform.

Health Care · Biotechnology: Pharmaceutical Preparations · 39 employees

About Instil Bio

TIL stock →

Instil Bio, Inc., a biopharmaceutical company, focuses on identifying and advancing therapeutic opportunities. It seeks to in-license or acquire and develop additional novel therapeutic candidates in diseases with significant unmet medical need.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 17 employees

HOWL vs TIL FAQ

Which is bigger, Werewolf Therapeutics or Instil Bio?

Instil Bio (TIL) is larger, with a market capitalization of $44.49M compared with $44.23M for Werewolf Therapeutics (HOWL).

Which stock has performed better over the past year, HOWL or TIL?

HOWL returned -51.60% over the past 12 months, compared with -68.05% for TIL (price return, excluding dividends). Past performance does not predict future results.

Are Werewolf Therapeutics and Instil Bio in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for Werewolf Therapeutics and Biotechnology: Biological Products (No Diagnostic Substances) for Instil Bio.

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