MetaCap

Hyperion DeFi (HYPD) vs Serina Therapeutics (SER)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Hyperion DeFi (HYPD) has outperformed Serina Therapeutics (SER) over the past year, losing 61.6% versus a loss of 62.8%. Over five years, SER leads with a -93.9% price change compared with -99.2% for HYPD. Hyperion DeFi is the larger company by market cap ($51.5 million vs $51.3 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

HYPD-61.60%SER-62.78%
+8%-36%-80%
Oct 7, 20251 yearOct 7, 2026
HYPD-99.18%SER-93.77%
+28%-39%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

HYPD versus SER key metrics
MetricHYPDSER
Share price$3.39$2.02
Market cap$51.53M$51.31M
1-day change-5.61%+0.23%
YTD return+0.84%+5.07%
1-year return-61.60%-62.78%
5-year return-99.15%-93.88%
EPS (TTM)$-6.46$-1.87
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$9.50$5.71
52-week low$2.34$1.22
Distance from 52-week high-64.32%-64.63%
Average volume445.34K64.02K
Shares outstanding15.20M25.40M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

HYPD vs SER FAQ

Which is bigger, Hyperion DeFi or Serina Therapeutics?

Hyperion DeFi (HYPD) is larger, with a market capitalization of $51.53M compared with $51.31M for Serina Therapeutics (SER).

Which stock has performed better over the past year, HYPD or SER?

HYPD returned -61.60% over the past 12 months, compared with -62.78% for SER (price return, excluding dividends). Past performance does not predict future results.

Are Hyperion DeFi and Serina Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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