Inspire Medical Systems (INSP) vs Pulse Biosciences (PLSE)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Pulse Biosciences (PLSE) has outperformed Inspire Medical Systems (INSP) over the past year, gaining 150.7% versus a loss of 15.1%. Over five years, PLSE leads with a +130.9% price change compared with -72.8% for INSP. Pulse Biosciences is the larger company by market cap ($3.84 billion vs $1.99 billion), about 1.9 times the size.
Inspire Medical Systems converts more of its revenue into profit, with a net margin of 15.9% versus -20794.6%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | INSP | PLSE |
|---|---|---|
| Share price | $68.89 | $53.81 |
| Market cap | $1.99B | $3.84B |
| 1-day change | +3.30% | +7.66% |
| YTD return | -27.69% | +264.02% |
| 1-year return | -15.09% | +150.65% |
| 5-year return | -72.80% | +130.85% |
| P/E ratio (TTM) | 15.17 | — |
| Forward P/E | 44.59 | — |
| EPS (TTM) | $4.54 | $-1.18 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $911.98M | $350.00K |
| Revenue growth (YoY) | +13.60% | — |
| Net income (latest FY) | $145.42M | $-72.78M |
| Gross margin | 85.39% | -54.00% |
| Operating margin | 5.59% | -21982.57% |
| Net margin | 15.95% | -20794.57% |
| 52-week high | $147.03 | $58.90 |
| 52-week low | $38.91 | $12.56 |
| Distance from 52-week high | -53.15% | -8.64% |
| Analyst consensus | hold | strong_buy |
| Avg. price target upside | -5.65% | +5.00% |
| Average volume | 798.17K | 502.81K |
| Shares outstanding | 28.91M | 71.32M |
| Employees | 1,333 | 116 |
| Sector | Health Care | Health Care |
| Industry | Medical/Dental Instruments | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PLSE has outperformed INSP by 165.7 percentage points over the past year.
- Inspire Medical Systems is more profitable, keeping 15.9 cents of every revenue dollar as net income versus -20794.6 cents for Pulse Biosciences.
About Inspire Medical Systems
INSP stock →Inspire Medical Systems, Inc., a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA) in the United States and internationally. The company offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for patients with moderate to severe OSA.
Health Care · Medical/Dental Instruments · 1,333 employees
About Pulse Biosciences
PLSE stock →Pulse Biosciences, Inc. operates as a novel bioelectric medicine company.
Health Care · Medical/Dental Instruments · 116 employees
INSP vs PLSE FAQ
Which is bigger, Inspire Medical Systems or Pulse Biosciences?
Pulse Biosciences (PLSE) is larger, with a market capitalization of $3.84B compared with $1.99B for Inspire Medical Systems (INSP).
Which stock has performed better over the past year, INSP or PLSE?
PLSE returned +150.65% over the past 12 months, compared with -15.09% for INSP (price return, excluding dividends). Past performance does not predict future results.
Are Inspire Medical Systems and Pulse Biosciences in the same industry?
Yes. Both are classified in the Medical/Dental Instruments industry within the Health Care sector.