MetaCap

Kalaris Therapeutics (KLRS) vs LeonaBio (LONA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

LeonaBio (LONA) has outperformed Kalaris Therapeutics (KLRS) over the past year, gaining 46.7% versus a loss of 49.0%. Over five years, LONA leads with a -94.0% price change compared with -99.5% for KLRS. Kalaris Therapeutics is the larger company by market cap ($56.2 million vs $54.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

KLRS-48.97%LONA+46.68%
+210%+74%-61%
Oct 9, 20251 yearOct 9, 2026
KLRS-99.53%LONA-93.82%
+83%-13%-108%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

KLRS versus LONA key metrics
MetricKLRSLONA
Share price$2.36$5.75
Market cap$56.18M$54.17M
1-day change-5.60%0.00%
YTD return-72.04%-24.04%
1-year return-48.97%+46.68%
5-year return-99.54%-93.99%
EPS (TTM)$-2.02$-23.01
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$11.88$14.21
52-week low$2.35$2.21
Distance from 52-week high-80.13%-59.54%
Analyst consensusstrong_buynone
Avg. price target upside+692.80%+201.39%
Average volume254.36K185.88K
Shares outstanding23.80M9.42M
Employees2019
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • LONA has outperformed KLRS by 95.7 percentage points over the past year.

About Kalaris Therapeutics

KLRS stock →

Kalaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of treatments for prevalent retinal diseases. It develops TH103, a clinical-stage anti-vascular endothelial growth factor (VEGF) drug for the treatment of neovascular age-related macular degeneration (nAMD), which is in Phase 1b/2, as well as for the treatment of other exudative and neovascular retinal diseases.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 20 employees

About LeonaBio

LONA stock →

LeonaBio, Inc., clinical-stage biopharmaceutical company, engages in the development of novel therapeutics for high unmet medical needs, including treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis. The company's lead products include lasofoxifene and ATH-1105, a novel small molecule therapies with the potential to address devastating diseases where current treatment options are limited or ineffective.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 19 employees

KLRS vs LONA FAQ

Which is bigger, Kalaris Therapeutics or LeonaBio?

Kalaris Therapeutics (KLRS) is larger, with a market capitalization of $56.18M compared with $54.17M for LeonaBio (LONA).

Which stock has performed better over the past year, KLRS or LONA?

LONA returned +46.68% over the past 12 months, compared with -48.97% for KLRS (price return, excluding dividends). Past performance does not predict future results.

Are Kalaris Therapeutics and LeonaBio in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

More comparisons