MAIA Biotechnology (MAIA) vs Spero Therapeutics (SPRO)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
MAIA Biotechnology (MAIA) has outperformed Spero Therapeutics (SPRO) over the past year, losing 34.1% versus a loss of 45.8%. MAIA Biotechnology is the larger company by market cap ($70.4 million vs $67.3 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | MAIA | SPRO |
|---|---|---|
| Share price | $1.14 | $1.16 |
| Market cap | $70.39M | $67.26M |
| 1-day change | -3.40% | -1.28% |
| YTD return | -22.88% | -49.79% |
| 1-year return | -34.08% | -45.83% |
| 5-year return | — | -93.13% |
| P/E ratio (TTM) | — | 8.25 |
| Forward P/E | 1.03 | — |
| EPS (TTM) | $-0.62 | $0.14 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.19 | $3.08 |
| 52-week low | $0.87 | $1.08 |
| Distance from 52-week high | -64.26% | -62.50% |
| Average volume | 525.87K | 1.20M |
| Shares outstanding | 61.74M | 58.23M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- MAIA has outperformed SPRO by 11.8 percentage points over the past year.
MAIA vs SPRO FAQ
Which is bigger, MAIA Biotechnology or Spero Therapeutics?
MAIA Biotechnology (MAIA) is larger, with a market capitalization of $70.39M compared with $67.26M for Spero Therapeutics (SPRO).
Which stock has performed better over the past year, MAIA or SPRO?
MAIA returned -34.08% over the past 12 months, compared with -45.83% for SPRO (price return, excluding dividends). Past performance does not predict future results.
Are MAIA Biotechnology and Spero Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.