Spero Therapeutics (SPRO) vs Tenax Therapeutics (TENX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Spero Therapeutics (SPRO) has outperformed Tenax Therapeutics (TENX) over the past year, losing 45.8% versus a loss of 74.5%. Over five years, SPRO leads with a -93.1% price change compared with -99.9% for TENX. Tenax Therapeutics is the larger company by market cap ($71.5 million vs $68.1 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | SPRO | TENX |
|---|---|---|
| Share price | $1.17 | $1.91 |
| Market cap | $68.13M | $71.48M |
| 1-day change | -1.68% | -1.04% |
| YTD return | -49.79% | -84.33% |
| 1-year return | -45.83% | -74.50% |
| 5-year return | -93.13% | -99.93% |
| P/E ratio (TTM) | 8.36 | — |
| EPS (TTM) | $0.14 | $-1.48 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.08 | $19.40 |
| 52-week low | $1.08 | $1.31 |
| Distance from 52-week high | -62.01% | -90.15% |
| Average volume | 1.21M | 5.52M |
| Shares outstanding | 58.23M | 37.42M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- SPRO has outperformed TENX by 28.7 percentage points over the past year.
SPRO vs TENX FAQ
Which is bigger, Spero Therapeutics or Tenax Therapeutics?
Tenax Therapeutics (TENX) is larger, with a market capitalization of $71.48M compared with $68.13M for Spero Therapeutics (SPRO).
Which stock has performed better over the past year, SPRO or TENX?
SPRO returned -45.83% over the past 12 months, compared with -74.50% for TENX (price return, excluding dividends). Past performance does not predict future results.
Are Spero Therapeutics and Tenax Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.