MetaCap

Myriad Genetics (MYGN) vs Oruka Therapeutics (ORKA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Oruka Therapeutics (ORKA) has outperformed Myriad Genetics (MYGN) over the past year, gaining 241.6% versus a loss of 45.0%. Over five years, ORKA leads with a +130.8% price change compared with -86.8% for MYGN. Oruka Therapeutics is the larger company by market cap ($5.12 billion vs $401.7 million), about 12.7 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

MYGN-45.03%ORKA+241.64%
+423%+169%-86%
Oct 8, 20251 yearOct 8, 2026
MYGN-86.40%ORKA+137.64%
+258%+75%-107%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

MYGN versus ORKA key metrics
MetricMYGNORKA
Share price$4.20$77.28
Market cap$401.73M$5.12B
1-day change-1.87%-2.79%
YTD return-31.71%+154.97%
1-year return-45.03%+241.64%
5-year return-86.77%+130.82%
EPS (TTM)$-1.18$-2.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Net income (latest FY)—$-105.43M
52-week high$8.59$115.52
52-week low$2.74$24.31
Distance from 52-week high-51.11%-33.10%
Analyst consensusholdstrong_buy
Avg. price target upside-6.90%+100.57%
Average volume2.02M896.59K
Shares outstanding95.65M66.21M
Employees2,70068
SectorHealth CareHealth Care
IndustryBiotechnology: In Vitro & In Vivo Diagnostic SubstancesBiotechnology: In Vitro & In Vivo Diagnostic Substances

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Oruka Therapeutics is about 12.7 times larger than Myriad Genetics by market value ($5.12B vs $401.73M).
  • ORKA has outperformed MYGN by 286.7 percentage points over the past year.

About Myriad Genetics

MYGN stock →

Myriad Genetics, Inc., a molecular diagnostics and precision medicine company, develops molecular tests. The company offers molecular diagnostic tests for oncology, women's health, and pharmacogenomics.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 2,700 employees

About Oruka Therapeutics

ORKA stock →

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 68 employees

MYGN vs ORKA FAQ

Which is bigger, Myriad Genetics or Oruka Therapeutics?

Oruka Therapeutics (ORKA) is larger, with a market capitalization of $5.12B compared with $401.73M for Myriad Genetics (MYGN).

Which stock has performed better over the past year, MYGN or ORKA?

ORKA returned +241.64% over the past 12 months, compared with -45.03% for MYGN (price return, excluding dividends). Past performance does not predict future results.

Are Myriad Genetics and Oruka Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: In Vitro & In Vivo Diagnostic Substances industry within the Health Care sector.

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