MetaCap

Neurogene (NGNE) vs Oculis (OCS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Neurogene (NGNE) has outperformed Oculis (OCS) over the past year, gaining 2.6% versus a loss of 56.4%. Over five years, OCS leads with a -11.8% price change compared with -81.6% for NGNE. Oculis is the larger company by market cap ($533.4 million vs $530.3 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

NGNE+2.59%OCS-56.42%
+72%+4%-63%
Oct 8, 20251 yearOct 8, 2026
NGNE-80.05%OCS-11.81%
+249%+69%-110%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

NGNE versus OCS key metrics
MetricNGNEOCS
Share price$26.50$8.66
Market cap$530.30M$533.35M
1-day change+2.44%+1.88%
YTD return+28.64%-56.63%
1-year return+2.59%-56.42%
5-year return-81.65%-11.81%
EPS (TTM)$-5.15$-1.74
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$43.66$34.48
52-week low$15.93$8.30
Distance from 52-week high-39.30%-74.88%
Analyst consensusnonestrong_buy
Avg. price target upside+193.89%+321.36%
Average volume247.13K257.00K
Shares outstanding20.01M61.59M
Employees13160
SectorHealthcareHealth Care
IndustryBiotechnologyBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • NGNE has outperformed OCS by 59.0 percentage points over the past year.
  • The two companies sit in different sectors: Neurogene in Healthcare and Oculis in Health Care.

About Neurogene

NGNE stock →

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease.

Healthcare · Biotechnology · 131 employees

About Oculis

OCS stock →

Oculis Holding AG, a clinical-stage biopharmaceutical company, develops drug candidates to treat ophthalmic, neuro-ophthalmic, and neurological diseases in Switzerland and internationally. The company's lead product candidate is OCS-01, a topical dexamethasone optireach formulation, which is in Phase 3 clinical trials for the treatment of diabetic macular edema; OCS-02, a topical biologic candidate that is in Phase 2b clinical trials for the treatment for dry eye disease; and OCS-05, a disease modifying neuroprotective agent for neurological damage with indications for glaucoma, dry age-related macular degeneration and diabetic retinopathy, and acute optic neuritis.

Health Care · Biotechnology: Pharmaceutical Preparations · 60 employees

NGNE vs OCS FAQ

Which is bigger, Neurogene or Oculis?

Oculis (OCS) is larger, with a market capitalization of $533.35M compared with $530.30M for Neurogene (NGNE).

Which stock has performed better over the past year, NGNE or OCS?

NGNE returned +2.59% over the past 12 months, compared with -56.42% for OCS (price return, excluding dividends). Past performance does not predict future results.

Are Neurogene and Oculis in the same industry?

No. Neurogene is in the Healthcare sector, while Oculis is in Health Care.

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