MetaCap

Nuvation Bio (NUVB) vs Zenas BioPharma (ZBIO)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Nuvation Bio (NUVB) has outperformed Zenas BioPharma (ZBIO) over the past year, gaining 33.3% versus a gain of 1.3%. Zenas BioPharma is the larger company by market cap ($1.78 billion vs $1.76 billion), about 1.0 times the size, while Nuvation Bio is growing revenue faster (+699.0% vs +100.0%). Nuvation Bio converts more of its revenue into profit, with a net margin of -325.3% versus -3777.4%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

NUVB+33.06%ZBIO+1.31%
+166%+58%-51%
Oct 8, 20251 yearOct 8, 2026
NUVB+63.93%ZBIO+44.57%
+223%+74%-75%
Sep 9, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

NUVB versus ZBIO key metrics
MetricNUVBZBIO
Share price$5.00$27.26
Market cap$1.76B$1.78B
1-day change+1.01%+3.89%
YTD return-44.20%-27.73%
1-year return+33.33%+1.31%
5-year return-47.64%—
EPS (TTM)$-0.44$-9.63
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$62.90M$10.00M
Revenue growth (YoY)+698.96%+100.00%
Net income (latest FY)$-204.63M$-377.74M
Operating margin-338.72%-3830.57%
Net margin-325.31%-3777.37%
52-week high$9.75$44.60
52-week low$3.36$13.50
Distance from 52-week high-48.72%-38.88%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+160.00%+75.64%
Average volume5.65M733.34K
Shares outstanding350.12M65.18M
Employees305167
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • NUVB has outperformed ZBIO by 32.0 percentage points over the past year.
  • Nuvation Bio is more profitable, keeping -325.3 cents of every revenue dollar as net income versus -3777.4 cents for Zenas BioPharma.
  • Nuvation Bio grew revenue faster in its latest fiscal year (+698.96% vs +100.00%).

About Nuvation Bio

NUVB stock →

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 305 employees

About Zenas BioPharma

ZBIO stock →

Zenas BioPharma, Inc., a clinical-stage biopharma company, engages in the development and commercialization of transformative immunology-based therapies. Its lead product candidate is obexelimab, a bifunctional monoclonal antibody designed to bind CD19 and Fc?RIIb for the treatment of various I&I diseases and various indications, including immunoglobulin G4-related disease, multiple sclerosis, and systemic lupus erythematosus.

Health Care · Biotechnology: Pharmaceutical Preparations · 167 employees

NUVB vs ZBIO FAQ

Which is bigger, Nuvation Bio or Zenas BioPharma?

Zenas BioPharma (ZBIO) is larger, with a market capitalization of $1.78B compared with $1.76B for Nuvation Bio (NUVB).

Which stock has performed better over the past year, NUVB or ZBIO?

NUVB returned +33.33% over the past 12 months, compared with +1.31% for ZBIO (price return, excluding dividends). Past performance does not predict future results.

Are Nuvation Bio and Zenas BioPharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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