Orchestra BioMed (OBIO) vs Tilray Brands (TLRY)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Orchestra BioMed (OBIO) has outperformed Tilray Brands (TLRY) over the past year, gaining 107.3% versus a loss of 78.3%. Over five years, OBIO leads with a -42.5% price change compared with -96.4% for TLRY. Tilray Brands is the larger company by market cap ($533.5 million vs $345.1 million), about 1.5 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | OBIO | TLRY |
|---|---|---|
| Share price | $5.74 | $3.61 |
| Market cap | $345.06M | $533.49M |
| 1-day change | +1.43% | -2.83% |
| YTD return | +36.39% | -58.86% |
| 1-year return | +107.33% | -78.27% |
| 5-year return | -42.54% | -96.37% |
| Forward P/E | — | 20.33 |
| EPS (TTM) | $-0.86 | $-1.09 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $6.50 | $23.20 |
| 52-week low | $2.78 | $3.38 |
| Distance from 52-week high | -11.68% | -84.44% |
| Analyst consensus | strong_buy | buy |
| Avg. price target upside | +116.51% | +98.34% |
| Average volume | 299.24K | 4.07M |
| Shares outstanding | 60.11M | 147.78M |
| Employees | 86 | 3,595 |
| Sector | Health Care | Health Care |
| Industry | Medicinal Chemicals and Botanical Products | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OBIO has outperformed TLRY by 185.6 percentage points over the past year.
About Orchestra BioMed
OBIO stock →Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States.
Health Care · Medicinal Chemicals and Botanical Products · 86 employees
About Tilray Brands
TLRY stock →Tilray Brands, Inc., a lifestyle consumer products company, engages in the research, cultivation, processing, and distribution of medical cannabis products in Canada, the United States, Europe, the Middle East, Africa, and internationally. The company operates through four segments: Beverage, Cannabis, Distribution, and Wellness.
Health Care · Medicinal Chemicals and Botanical Products · 3,595 employees
OBIO vs TLRY FAQ
Which is bigger, Orchestra BioMed or Tilray Brands?
Tilray Brands (TLRY) is larger, with a market capitalization of $533.49M compared with $345.06M for Orchestra BioMed (OBIO).
Which stock has performed better over the past year, OBIO or TLRY?
OBIO returned +107.33% over the past 12 months, compared with -78.27% for TLRY (price return, excluding dividends). Past performance does not predict future results.
Are Orchestra BioMed and Tilray Brands in the same industry?
Yes. Both are classified in the Medicinal Chemicals and Botanical Products industry within the Health Care sector.