Orchestra BioMed (OBIO) vs USANA Health Sciences (USNA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Orchestra BioMed (OBIO) has outperformed USANA Health Sciences (USNA) over the past year, gaining 107.3% versus a loss of 44.3%. Over five years, OBIO leads with a -42.5% price change compared with -85.2% for USNA. Orchestra BioMed is the larger company by market cap ($341.4 million vs $266.3 million), about 1.3 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | OBIO | USNA |
|---|---|---|
| Share price | $5.68 | $14.42 |
| Market cap | $341.40M | $266.34M |
| 1-day change | +0.35% | -1.74% |
| YTD return | +36.39% | -25.27% |
| 1-year return | +107.33% | -44.28% |
| 5-year return | -42.54% | -85.19% |
| Forward P/E | — | 8.14 |
| EPS (TTM) | $-0.86 | $-1.20 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $6.50 | $26.56 |
| 52-week low | $2.78 | $12.57 |
| Distance from 52-week high | -12.62% | -45.73% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +118.84% | +73.43% |
| Average volume | 299.24K | 185.65K |
| Shares outstanding | 60.11M | 18.48M |
| Employees | 86 | 1,570 |
| Sector | Health Care | Health Care |
| Industry | Medicinal Chemicals and Botanical Products | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OBIO has outperformed USNA by 151.6 percentage points over the past year.
About Orchestra BioMed
OBIO stock →Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States.
Health Care · Medicinal Chemicals and Botanical Products · 86 employees
About USANA Health Sciences
USNA stock →USANA Health Sciences, Inc. develops, manufactures, and sells science-based nutritional, personal care, and skincare products in the Asia Pacific, the Americas, and Europe.
Health Care · Medicinal Chemicals and Botanical Products · 1,570 employees
OBIO vs USNA FAQ
Which is bigger, Orchestra BioMed or USANA Health Sciences?
Orchestra BioMed (OBIO) is larger, with a market capitalization of $341.40M compared with $266.34M for USANA Health Sciences (USNA).
Which stock has performed better over the past year, OBIO or USNA?
OBIO returned +107.33% over the past 12 months, compared with -44.28% for USNA (price return, excluding dividends). Past performance does not predict future results.
Are Orchestra BioMed and USANA Health Sciences in the same industry?
Yes. Both are classified in the Medicinal Chemicals and Botanical Products industry within the Health Care sector.