MetaCap

Omeros (OMER) vs Tyra Biosciences (TYRA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Omeros (OMER) has outperformed Tyra Biosciences (TYRA) over the past year, gaining 335.5% versus a gain of 52.5%. Over five years, OMER leads with a +147.3% price change compared with +24.8% for TYRA. Omeros is the larger company by market cap ($1.38 billion vs $1.37 billion), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

OMER+322.30%TYRA+52.51%
+393%+183%-27%
Oct 7, 20251 yearOct 7, 2026
OMER+185.37%TYRA+25.40%
+214%+58%-98%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

OMER versus TYRA key metrics
MetricOMERTYRA
Share price$19.12$19.97
Market cap$1.38B$1.37B
1-day change+1.97%-2.06%
YTD return+11.29%-22.44%
1-year return+335.54%+52.51%
5-year return+147.35%+24.79%
P/E ratio (TTM)15.67—
Forward P/E15.54—
EPS (TTM)$1.22$-2.39
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$21.24$40.65
52-week low$4.06$13.29
Distance from 52-week high-9.98%-50.87%
Analyst consensusnonestrong_buy
Avg. price target upside+43.83%+137.61%
Average volume1.74M857.13K
Shares outstanding72.39M68.76M
Employees17587
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • OMER has outperformed TYRA by 283.0 percentage points over the past year.

About Omeros

OMER stock →

Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory distress syndrome.

Health Care · Biotechnology: Pharmaceutical Preparations · 175 employees

About Tyra Biosciences

TYRA stock →

Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions.

Health Care · Biotechnology: Pharmaceutical Preparations · 87 employees

OMER vs TYRA FAQ

Which is bigger, Omeros or Tyra Biosciences?

Omeros (OMER) is larger, with a market capitalization of $1.38B compared with $1.37B for Tyra Biosciences (TYRA).

Which stock has performed better over the past year, OMER or TYRA?

OMER returned +335.54% over the past 12 months, compared with +52.51% for TYRA (price return, excluding dividends). Past performance does not predict future results.

Are Omeros and Tyra Biosciences in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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