MetaCap

OPKO Health (OPK) vs Seaport Therapeutics (SPTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

OPKO Health is the larger company by market cap ($1.03 billion vs $975.3 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

OPK+24.55%SPTX-9.73%
+61%+17%-27%
May 1, 20261 yearOct 8, 2026
OPK+24.55%SPTX-9.73%
+55%+16%-23%
Apr 27, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

OPK versus SPTX key metrics
MetricOPKSPTX
Share price$1.39$18.22
Market cap$1.03B$975.33M
1-day change+1.09%+1.73%
YTD return+8.73%—
1-year return-11.61%—
5-year return-63.17%—
EPS (TTM)$-0.09$-5.81
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$1.75$28.38
52-week low$0.98$14.85
Distance from 52-week high-20.86%-35.80%
Analyst consensusnonestrong_buy
Avg. price target upside+216.25%+110.15%
Average volume3.35M182.45K
Shares outstanding746.33M53.53M
Employees2,27558
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About OPKO Health

OPK stock →

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 2,275 employees

About Seaport Therapeutics

SPTX stock →

Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. It is leveraging its proprietary Glyph platform to advance a pipeline of therapies to address the unmet needs in depression and anxiety.

Health Care · Biotechnology: Pharmaceutical Preparations · 58 employees

OPK vs SPTX FAQ

Which is bigger, OPKO Health or Seaport Therapeutics?

OPKO Health (OPK) is larger, with a market capitalization of $1.03B compared with $975.33M for Seaport Therapeutics (SPTX).

Are OPKO Health and Seaport Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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